[1]刘家秀,赵维佳,李玉叶.多次误诊的恶性萎缩性丘疹病1例[J].中国皮肤性病学杂志,2021,(09):1021.[doi:10.13735/j.cjdv.1001-7089.202011113]
 LIU Jiaxiu,ZHAO Weijia,LI Yuye.A Case of Malignant Atrophic Papulosis Misdiagnosed Repeatedly[J].The Chinese Journal of Dermatovenereology,2021,(09):1021.[doi:10.13735/j.cjdv.1001-7089.202011113]
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多次误诊的恶性萎缩性丘疹病1例()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年09期
页码:
1021
栏目:
病例报告
出版日期:
2021-09-01

文章信息/Info

Title:
A Case of Malignant Atrophic Papulosis Misdiagnosed Repeatedly
文章编号:
1001-7089(2021)09-1021-03
作者:
刘家秀赵维佳李玉叶
昆明医科大学第一附属医院皮肤性病科,云南 昆明 650000
Author(s):
LIU JiaxiuZHAO WeijiaLI Yuye
(Department of Dermatology and Venereology,the First Affiliated Hospital of Kunming Medical University,Kunming 650000,China)
关键词:
恶性萎缩性丘疹病 德戈斯病 灶性坏死 血管梗塞 误诊
Keywords:
Malignant atrophic papulosis Degos disease Focal necrosis Vascular infarction Misdiagnosis
分类号:
R 758.6
DOI:
10.13735/j.cjdv.1001-7089.202011113
文献标志码:
A
摘要:
患者男,56岁,全身散在丘疹、萎缩性瘢痕1年余。皮疹起初为粟粒至黄豆大小的丘疹,表面泛白,无脓点、破溃、糜烂,后丘疹中央逐渐出现萎缩,边缘隆起伴轻度水肿,最终形成瘢痕,表面附着薄层鳞屑。皮损组织病理示:表皮灶性坏死、结痂、变薄,基底层细胞液化变性,真皮浅层楔形胶原硬化,部分血管梗塞、坏死。诊断:恶性萎缩性丘疹病。患者经双嘧达莫、沙利度胺、灯盏生脉胶囊口服治疗,未见明显好转。
Abstract:
A 56-year-old male presented with scattered papules and atrophic scars all over the body for more than one year.The rash was initially a papule with the size of a miliary to a soybean.The surface was white with no pus,ulceration,or erosion.The center of the papule gradually shrinked,the edge was raised with mild edema,and finally a scar was formed with a thin layer of scale attached to the surface.Pathology of the skin lesion showed epidermal focal necrosis,scab,thinning,liquefaction and degeneration of basal cells,sclerosis of wedge-shaped collagen in the superficial dermis,and partial vascular infarction and necrosis.Diagnosis of malignant atrophic papulosis was made.Oral treatment of dipyridamole,thalidomide,and Dengzhan Shengmai capsules did not contribute to any significant improvement.

参考文献/References:

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 WANG Danxu,MIN Zhongsheng,XU Yan,et al.A Case of Malignant Atrophic Papulosis and Literature Review[J].The Chinese Journal of Dermatovenereology,2018,(09):61.[doi:10.13735/j.cjdv.1001-7089.201706061]

备注/Memo

备注/Memo:
[基金项目] 云南省“万人计划”名医专项; 云南省卫生和计划生育委员会医学领军人才(L-201613); 云南省皮肤免疫疾病临床医学研究中心(2019ZF012); 云南省皮肤免疫性疾病临床医学中心(ZX2019-03-02)
[通信作者] 李玉叶,E-mail:yyeli2000@126.com
更新日期/Last Update: 2021-09-01