[1]王雪,杨智,段晓霞,等.无创性检测技术在皮肤光老化中的应用[J].中国皮肤性病学杂志,2021,(03):333-338.[doi:10.13735/j.cjdv.1001-7089.202003153]
 WANG Xue,YANG Zhi,DUAN Xiaoxia,et al.Non-invasive Detection Technology in Skin Photoaging[J].The Chinese Journal of Dermatovenereology,2021,(03):333-338.[doi:10.13735/j.cjdv.1001-7089.202003153]
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无创性检测技术在皮肤光老化中的应用()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年03期
页码:
333-338
栏目:
综述
出版日期:
2021-03-01

文章信息/Info

Title:
Non-invasive Detection Technology in Skin Photoaging
文章编号:
1001-7089(2021)03-0333-06
作者:
王雪杨智段晓霞郭碧润向顺俪徐琪
昆明医科大学第一附属医院皮肤性病科,云南 昆明 650032
Author(s):
WANG XueYANG ZhiDUAN XiaoxiaGUO BirunXIANG ShunliXU Qi
(Department of Dermatology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)
关键词:
光老化 无创检测 应用
Keywords:
Photoaging Non-invasive technique Application
分类号:
R 751
DOI:
10.13735/j.cjdv.1001-7089.202003153
文献标志码:
A
摘要:
光老化是指皮肤长期受紫外线(ultraviolet,UV)辐射所引起的皮肤老化。光老化皮肤主要表现为毛细血管扩张、粗糙干燥、松弛、皱纹加深、色素沉着,甚至可能出现各种良性或恶性肿瘤。大量研究对光老化皮肤的变化从各个方面进行描述和评估,如临床肉眼评估、组织病理及免疫组织化学检查等。随着科技的发展,无创检测技术在皮肤光老化中的应用逐渐增多。本文将综述各种无创检测技术在皮肤光老化中的应用。
Abstract:
Photoaging defined as skin aging caused by long-term ultraviolet(UV)radiation.The main manifestations of photoaging are telangiectasia, rough and dry, loose, deepened wrinkles, pigmentation, and various benign or malignant tumors.A large number of studies have described and evaluated the changes of photoaging,such as clinical, histopathology and immunohistochemistry evaluation.With the development of science and technology, the application of non-invasive technique in photoaging has been increasing.This paper will review the application of non-invasive technique in photoaging.

参考文献/References:

[1] Fisher GJ, Wang ZQ, Datta SC, et al.Pathophysiology of premature skin aging induced by ultraviolet light[J].N Engl J Med, 1997, 337(20): 1419-1429.
[2] Shin D, Lee Y, Huang Y, et al.Probiotic fermentation augments the skin anti-photoaging properties of Agastache rugosa through up-regulating antioxidant components in UVB-irradiated HaCaT keratinocytes[J].BMC Complement Altern Med, 2018, 18(1): 1-10.
[3] 刘国宁,陈斌.皮肤老化中弹性组织变性机制的研究进展[J].临床皮肤科杂志,2013,42(5):325-328.
[4] Imokawa G, Ishida K.Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging I: reduced skin elasticity, highly associated with enhanced dermal elastase activity, triggers wrinkling and sagging[J].Int J Mol Sci, 2015, 16(4): 7753-7775.
[5] Argenziano G, Soyer HP.Dermoscopy of pigmented skin lesions- a valuable tool for early[J].Lancet Oncol, 2001, 2(7): 443-449.
[6] Hu SC, Lin C, Yu H, et al.Dermoscopic assessment of xerosis severity, pigmentation pattern and vascular morphology in subjects with physiological aging and photoaging[J].Eur J Dermatol, 2019, 29(3): 274-280.
[7] Isik B, Gurel MS, Erdemir AT,et al.Development of skin aging scale by using dermoscopy[J].Skin Res Technol, 2013, 19(2): 69-74.
[8] Elsayed MH, Saleh HM, Zawahry KM, et al.The dermoscopic features of facial aging among Egyptians: A com-parative study between males and females[J].J Cosmet Dermatol, 2019, 18(6): 1803-1813.
[9] 董依云,周国瑜.非创伤性检测技术在光老化皮肤治疗中的应用进展[J].中国美容医学,2012,21(11):1665-1668.
[10] Sauermann K, Clemann S, Jaspers S, et al.Age related changes of human skin investigated with histometric measure-ments by confocal laser scanning microscopy in vivo[J].Skin Res Technol, 2002, 8(1): 52-56.
[11] Yamashita T, Akita H, Astner S, et al.In vivo assessment of pigmentary and vascular compartments changes in UVA exposed skin by reflectance-mode confocal microscopy[J].Exp Dermatol, 2007, 16(11): 905-911.
[12] Haytoglu NS, Gurel MS, Erdemir AT, et al.Assessment of skin photoaging with reflectance confocal microscopy[J].Skin Res Technol, 2014, 20(3): 363-372.
[13] Wurm E, Longo C, Curchin C,et al.In vivo assessment of chronological ageing and photoageing in forearm skin using reflflectance confocal microscopy[J].Br J Dermatol, 2012, 167(2): 270-279.
[14] Koehler M J, Konig K, Elsner P, et al.In vivo assessment of human skin aging by multiphoton laser scanning tomography[J].Opt Lett, 2006, 31(19): 2879-2881.
[15] Lin SJ, Wu RJ, Tan HY, et al.Evaluating cutaneous photo-aging by use of multiphoton fluorescence and secondhar-monic generation microscopy[J].Opt Lett, 2005, 30(17): 2275-2277.
[16] Sugata K, Osanai O, Sano T, et al.Evaluation of photo-aging in facial skin by multiphoton laser scanning micro-scopy[J].Skin Res Technol, 2011, 17(1): 1-3.
[17] Puschmann S, Rahn CD, Wenck H, et al.Approach to quantify human dermal skin aging using multiphoton laser scanning microscopy[J].J Biomed Opt, 2012, 17(3): 036005.
[18] Konig K, Uchugonova A, Gorjup E, et al.Multiphoton fluorescence lifetime imaging of 3D-stem cell spheroids during differentiation[J].Microsc Res Tech, 2011, 74(1): 9-17.
[19] Nogueira MS, Kurachi C.Assessing the photoaging process at sun exposed and non-exposed skin using fluorescence lifetime spectroscopy[C].Proceedings of SPIE, 2016.
[20] Gonzalez FJ, Castillomartinez C, Martinezescaname M, et al.Noninvasive estimation of chronological and photoinduced skin damage using Raman spectroscopy and principal component analysis[J].Skin Res Technol, 2012, 18(4): 442-446.
[21] Caetano LD, Mendes TD, Bagatin E, et al.In vivo confocal Raman spectroscopy for intrinsic aging and photoaging assessment[J].J Dermatol Sci,2017, 88(2): 199-206.
[22] Edward Z,Povazay B,Laufer J.Multimodal photo-acoustic and optical coherence tomography scanner using anall optical detection scheme for 3D morphological skin imaging[J].Biomed Opt Express, 2011,2(8): 2202-2215.
[23] Gambichler T,Jaedicke V,Teltas S.Optical coherence tomogxaphy in dermatology:technical and elinical aspects[J].Arch Dermatol Res,2011,303(7):457-473.
[24] Mamalis A, Ho D, Jagdeo J, et al.Opticalcoherence tomography imaging of normal, chronologically aged, photoaged and photodamaged skin: a systematic review[J].Dermatol Surg, 2015, 41(9): 993-1005.
[25] Barton JK, Gossage KW, Xu W, et al.Investigating sun-damaged skin and actinic keratosis with optical coherence tomography: a pilot study[J].Technol Cancer Res Treat, 2003, 2(6): 525-535.
[26] Wu S, Li H, Zhang X, et al.Optical features for chronological aging and photoaging skin by opticalcoherence tomography[J].Lasers Med Sci, 2013, 28(2): 445-450.
[27] Sandbymoller J, Wulf HC.Ultrasonographic subepidermal low-echogenic band, dependence of age and body site[J].Skin Res Technol, 2004, 10(1): 57-63.
[28] Lee HK,Seo YK,Baek JH,et al.Comparison between ultrasonography(Dermascan C version 3)and trans-parency profilometry(Skin Visiometer SV600)[J].Skin Res Technol,2008,14(1):8-12.
[29] de Rigal J, Escoffifier C, Querleux B, et al.Assessment of aging of the human skin by in vivo ultrasound imaging[J].J Invest Dermatol,1989,93(5):621-625.
[30] Gniadecka M.Effects of ageing on dermal echogenicity[J].Skin Res Technol,2001,7(3):204-207.
[31] Gniadecka M, Jemec GB.Quantitative evaluation of chro-nological ageing and photoageing in vivo: studies on skin echogenicity and thickness[J].Br J Dermatol, 1998, 139(5): 815-821.
[32] Sandbymoller J, Thieden E, Philipsen PA, et al.Dermal echogenicity: a biological indicator of individual cumulative UVR exposure?[J].Arch Dermatol Res, 2004, 295(11): 498-504.
[33] Caetano LD, Soares JL, Bagatin E, et al.Reliable assessment of forearm photoageing by high-frequency ultrasound: a cross-sectional study[J].Int J Cosmet Sci, 2016, 38(2): 170-177.
[34] Altman AM, Bankson JA, Matthias N, et al.Magnetic resonance imaging as a novel method of characterization of cutaneous photoaging in a murine model[J].Arch Dermatol Res, 2008, 300(5): 263-267.
[35] 赵琛,朱威,连石.北京地区176名健康女性面部皮肤自然老化和光老化特征分析[J].现代医学,2013,41(1):19-22.
[36] Quan MB, Edwards C, Marks R, et al.Non-invasive in vivo techniques to differentiate photodamage and ageing in human skin[J].Acta Derm Venereol, 1997, 77(6): 416-419.
[37] Battistutta D, Pandeya N, Strutton G, et al.Skin surface topography grading is a valid measure of skin photoaging[J].Photodermatol Photoimmunol Photomed, 2006, 22(1): 39-45.
[38] Fritschi L, Battistutta D, Strutton GM, et al.A non-invasive measure of photoageing[J].Int J Epidemiol,1995, 24(1):150-154.
[39] 陈旭,孔佩慧,甄雅贤.电容成像技术研究皮肤光老化[J].中华皮肤科杂志,2013,46(5):373-374.
[40] Kaczvinsky JR, Griffiths CE, Schnicker MS, et al.Efficacy of antiaging products for periorbital wrinkles as measured by 3D imaging [J].J Cosmet Dennatol, 2009, 8(3): 228-233.
[41] Merinville E, Byrne AJ, Rawlings AV, et al.Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin [J].J Cosmet Dermatol, 2010, 9(3): 174-184.
[42] Li L, Macmary S, Marsaut D, et al.Age-related changes in skin topography and microcirculation[J].Arch Dermatol Res, 2006, 297(9): 412-416.

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备注/Memo

备注/Memo:
[基金项目] 省基础研究计划 2019FE001( -204); 云南省高层次卫生计生技术人才培养经费资助
[通信作者] 杨智,E-mail: vipyz@126.com
更新日期/Last Update: 2021-02-10