[1]黄新绿,杜娟,王芳,等.肢端黑素瘤合并骨髓增生异常综合征1例[J].中国皮肤性病学杂志,2021,(03):306-308.[doi:10.13735/j.cjdv.1001-7089.202006106]
 HUANG Xinlyu,DU Juan,WANG Fang,et al.Acral Melanoma with Myelodysplastic Syndrome: A Case Report[J].The Chinese Journal of Dermatovenereology,2021,(03):306-308.[doi:10.13735/j.cjdv.1001-7089.202006106]
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肢端黑素瘤合并骨髓增生异常综合征1例()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年03期
页码:
306-308
栏目:
病例报告
出版日期:
2021-03-01

文章信息/Info

Title:
Acral Melanoma with Myelodysplastic Syndrome: A Case Report
文章编号:
1001-7089(2021)03-0306-03
作者:
黄新绿杜娟王芳金江
北京大学人民医院皮肤科,北京 100044
Author(s):
HUANG XinlyuDU JuanWANG FangJIN Jiang
(Department of Dermatology,Peking University People's Hospital,Beijing 100044,China)
关键词:
肢端黑素瘤 骨髓增生异常综合征 肾母细胞瘤抑制基因 黑素瘤优先表达抗原
Keywords:
Acral melanoma Myelodysplastic syndromes WT gene PRAME
分类号:
R 551.3; R 739.5
DOI:
10.13735/j.cjdv.1001-7089.202006106
文献标志码:
B
摘要:
患者男,67岁,发现右足底黑斑和肿物2个月,迅速增大10 d。患者1年前确诊骨髓增生异常综合征-EB1型。皮肤科情况:右足底单发肿物,表面颜色不均,伴糜烂,周围形状不规则的浅褐色至深褐色斑片。组织病理提示:黑素细胞瘤,梭形细胞型。免疫组织化学显示:S-100(+),SOX-10(+)。建议行右足底皮肤恶性肿瘤扩大切除术,患者拒绝。3个月后患者死亡,死因不详。
Abstract:
A 67-year-old male complained of a rapid-onset nodule with mild pain on his right plantar for ten days.He had a history of myelodysplastic syndrome(MDS)-EB1 for one year.Physical examination revealed a nodule on his right plantar, with irregularly bordered, black-brown and unevenly discolored patch around the nodule.Skin biopsy showed spindle melanoma cells.Immunostaining displayed the cells positive staining for S-100 and SOX-10.The patient refused to perform wide local excision and died unfortunately after a 3-month follow-up.

参考文献/References:

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更新日期/Last Update: 2021-02-10