[1]周彦君,熊心猜.色素减退型蕈样肉芽肿1例[J].中国皮肤性病学杂志,2021,(03):300-303.[doi:10.13735/j.cjdv.1001-7089.201911095]
 ZHOU Yanjun,XIONG Xincai.Hypopigmented Mycosis Fungoides: A Case Report[J].The Chinese Journal of Dermatovenereology,2021,(03):300-303.[doi:10.13735/j.cjdv.1001-7089.201911095]
点击复制

色素减退型蕈样肉芽肿1例()
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年03期
页码:
300-303
栏目:
病例报告
出版日期:
2021-03-01

文章信息/Info

Title:
Hypopigmented Mycosis Fungoides: A Case Report
文章编号:
1001-7089(2021)03-0300-04
作者:
周彦君熊心猜
川北医学院附属医院皮肤科,四川 南充 637000
Author(s):
ZHOU YanjunXIONG Xincai
(Department of Dermatology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)
关键词:
蕈样肉芽肿 色素减退 异型淋巴样细胞
Keywords:
Mycosis fungoides Hypopigmented Heteromorphic lymphoid cell
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201911095
文献标志码:
B
摘要:
患者女,45岁,2年前无明显原因躯干出现色素减退斑,无自觉症状,2年内色素减退斑逐渐增多且累及颈部、四肢。皮肤科情况:全身泛发形状不规则、大小不一的色素减退性浸润性斑片,边界较模糊。皮损组织病理示:表皮内可见多个核大、深染、周围有空晕的异型淋巴样细胞,亲表皮现象比较明显。免疫组织化学提示表皮内CD8+T淋巴细胞浸润。诊断:色素减退型蕈样肉芽肿。
Abstract:
A 45-year-old female presented with growing hypopigmented macules on the neck, truncus and limbs for 2 years, and it without obvious symptoms.Dermatologic examination showed generalized hypopigmented infiltrating patches without clear margin on the whole body.Skin biopsy revealed intense epidermotropism, and many heteromorphic lymphoid cells with large nuclei, the cells with deep staining and surrounding empty halo could be found in the epidermis.Immunohistochemistry examination showed CD8+T lymphocytes infiltrate within epidermal.Diagnosis of hypopigmented mycosis fungoides was made.

参考文献/References:

[1] 赵辨.中国临床皮肤病学[M].2版.南京:江苏凤凰科学技术出版社,2017:1875.
[2] Naeini FF,Soghrati M,Abtahi-Naeini B,et al.Co-existence of various clinical and histopathological features of mycosis fungoides in a young female[J].Indian J Dermatol,2014,60(2):214.
[3] Farahnaz FN,Bahareh AN,Hamidreza S,et al.Mycosis fungoides in iranian population: an epidemiological and cli-nicopathological study[J].J Skin Cancer,2015,2015:1-6.
[4] Ryan EA,Sanderson KV,Barták P,et al.Can mycosis fungoides begin in the epidermis? A hypothesis[J].Br J Dermatol,1973,88(5): 419-429.
[5] Furlan FC,Sanches JA.Hypopigmented mycosis fungoides: a review of its clinical features and pathophysiology[J].An Bras Dermatol,2013,88(6): 954-960.
[6] 余时娟,任发亮,王华.色素减退型蕈样肉芽肿的研究进展[J].儿科药学杂志,2019,25(10):62-66.
[7] 任发亮,白晓明,蒋金秋,等.儿童色素减退型蕈样肉芽肿1例[J].中国皮肤性病学杂志,2018,32(10):82-85.
[8] Ayako I,Kazunari S,Ayano I,et al.CD4/CD8 double-negative mycosis fungoides: a case report and literature review[J].Yonago Acta Med,2019,62(1): 153-158.
[9] Boulos S,Vaid R,Aladily TN,et al.Clinical presentation,immunopathology,and treatment of juvenile-onset mycosis fungoides: A case series of 34 patients[J].J Am Acad Dermatol,2014,71(6):1117-1126.
[10] Bisherwal K,Singal A,Pandhi D,et al.Hypopigmented mycosis fungoides: clinical,histological,and immunohistochemical remission induced by narrow-band ultraviolet B[J].Indian J Dermatol,2017,62(2):203-206.

相似文献/References:

[1]谭灵芝,王晓龙,韩世新,等.表现为糜烂性斑块的蕈样肉芽肿1例[J].中国皮肤性病学杂志,2016,(08):820.[doi:10.13735/j.cjdv.1001-7089.201512110]
 TAN Ling-zhi,WANG Xiao-long,HAN Shi-xin,et al.A Case of Mycosis Fungoides Presenting as Erosive Plaques[J].The Chinese Journal of Dermatovenereology,2016,(03):820.[doi:10.13735/j.cjdv.1001-7089.201512110]
[2]武奕,石春蕊,余炳前,等.蕈样肉芽肿并内脏占位病变误诊为湿疹和银屑病1例[J].中国皮肤性病学杂志,2018,(02):231.[doi:10.13735/j.cjdv.1001-7089.201706043]
 WU Yi,SHI Chunrui,YU Bingqian,et al.A Case of Mycosis Fungoides with Visceral Lesions Misdiagnosed as Eczema or Psoriasis[J].The Chinese Journal of Dermatovenereology,2018,(03):231.[doi:10.13735/j.cjdv.1001-7089.201706043]
[3]苏蓓蓓*,王涛,刘跃华,等.鱼鳞病样蕈样肉芽肿1例[J].中国皮肤性病学杂志,2018,(04):423.[doi:10.13735/j.cjdv.1001-7089.201703150]
 SU Beibei*,WANG Tao,LIU Yuehua,et al.A Case of Ichthyosiform Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2018,(03):423.[doi:10.13735/j.cjdv.1001-7089.201703150]
[4]张文文,王小康,赵双莉,等.弥漫性色素沉着伴点状色素减退1例[J].中国皮肤性病学杂志,2018,(04):426.[doi:10.13735/j.cjdv.1001-7089.201707129]
 ZHANG Wenwen,WANG Xiaokang,ZHAO Shuangli,et al.A Case of Diffuse Hyperpigmentation with Guttate Depigmented Macules[J].The Chinese Journal of Dermatovenereology,2018,(03):426.[doi:10.13735/j.cjdv.1001-7089.201707129]
[5]祝守敏,汪旸,涂平.亲毛囊性蕈样肉芽肿研究进展[J].中国皮肤性病学杂志,2014,(06):634.[doi:10.13735/j.cjdv.1001-7089.2014.0634]
 ZHU Shou-min,WANG Yang,TU Ping.Advanes of Folliculotropic Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2014,(03):634.[doi:10.13735/j.cjdv.1001-7089.2014.0634]
[6]华夏,解瑶,陈小玫,等.伴大细胞转化的蕈样肉芽肿1例[J].中国皮肤性病学杂志,2014,(03):287.
 HUA Xia,XIE Yao,CHEN Xiao-mei,et al.A Case of Large Cell Transformation of Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2014,(03):287.
[7]任发亮,白晓明,蒋金秋,等.儿童色素减退型蕈样肉芽肿1例[J].中国皮肤性病学杂志,2018,(10):1180.[doi:10.13735/j.cjdv.1001-7089.201802048]
 REN Faliang,BAI Xiaoming,JIANG Jinqiu,et al.A Case of Pediatric Hypopigmented Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2018,(03):1180.[doi:10.13735/j.cjdv.1001-7089.201802048]
[8]王懿珊,于晓虹,韩世新,等.红皮病型蕈样肉芽肿1例[J].中国皮肤性病学杂志,2019,(12):1412.[doi:10.13735/j.cjdv.1001-7089.201901101]
 WANG Yishan,YU Xiaohong,HAN Shixin,et al.A Case of Erythrodermic Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2019,(03):1412.[doi:10.13735/j.cjdv.1001-7089.201901101]
[9]顾安康,张秀君,马法库,等.糖皮质激素局部封闭致色素减退中黑素细胞数量及功能的变化[J].中国皮肤性病学杂志,2020,(10):1121.[doi:10.13735/j.cjdv.1001-7089.202001085]
 GU Ankang,ZHANG Xiujun,MA Faku,et al.Changes in the Number and Function of Melanocytes in Hypopigmentation Induced by Local Glucocorticoid Blockage[J].The Chinese Journal of Dermatovenereology,2020,(03):1121.[doi:10.13735/j.cjdv.1001-7089.202001085]
[10]张颖,冯林,江阳,等.异色病样蕈样肉芽肿1例[J].中国皮肤性病学杂志,2020,(11):1310.[doi:10.13735/j.cjdv.1001-7089.201912026]
 ZHANG Ying,FENG Lin,JIANG Yang,et al.A Case of Poikilodermatous Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2020,(03):1310.[doi:10.13735/j.cjdv.1001-7089.201912026]

更新日期/Last Update: 2021-02-10