[1]胡瑜霞,魏娇,熊潇,等.阴囊皮脂腺癌1例[J].中国皮肤性病学杂志,2021,(02):196-199.
 HU Yuxia,WEI Jiao,XIONG Xiao,et al.A Case of Scrotal Sebaceous Carcinoma[J].The Chinese Journal of Dermatovenereology,2021,(02):196-199.
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阴囊皮脂腺癌1例()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年02期
页码:
196-199
栏目:
病例报告
出版日期:
2021-02-01

文章信息/Info

Title:
A Case of Scrotal Sebaceous Carcinoma
文章编号:
1001-7089(2021)02-0196-04
作者:
胡瑜霞魏娇熊潇李翠婷刘劲松刘菡
湖北医药学院附属东风医院皮肤性病科,湖北 十堰 442000
Author(s):
HU YuxiaWEI JiaoXIONG XiaoLI CuitingLIU JinsongLIU Han
(Department of Dermatology,Affiliated Dongfeng Hospital,Hubei University of Medicine,Shiyan 442000,China)
关键词:
阴囊 皮脂腺癌 组织病理学
Keywords:
Scrotal Sebaceous carcinoma Histopathology
分类号:
R 739.5
文献标志码:
B
摘要:
患者男,72岁,双侧阴囊反复红斑伴痒2年余,新发肿块2个月。皮肤科情况:双侧阴囊见局限性境界清楚的浸润性暗红斑,表面有浅糜烂、渗液; 右侧阴囊红斑皮损上见一处约1.5 cm×1.0 cm×0.3 cm大小的暗红色肿块,大致呈半球状,触之质稍硬,表面不光滑,活动度尚可。皮损组织病理示:真皮内肿瘤细胞呈巢团状分布,胞浆丰富、呈嗜酸性,核仁明显,可见核分裂象,中间有纤维间隔,于皮肤附属器周围浸润,周围表皮内可见Paget病样播散的肿瘤细胞。免疫组织化学:EMA、CKpan、CKL、CK7、AR、CD15、CA153阳性,CK14、CK17、CK20、CEA、Mamaglobin、GCDFP-15、CD34、D2-40阴性,Ki67增殖指数为30%。诊断:阴囊皮脂腺癌。
Abstract:
A 72-year-old male presented bilateral scrotum recurrent erythema with pruritus for more than 2 years,new mass for 2 months.Physical examination revealed infiltrating dark erythema with localized boundary,superficial erosion and exudation on the scrotum.On the erythema lesions of right scrotal had a dark red mass,with non-smooth surface,slightly stiffly touched and good activity in shape of roughly hemisphere and size of 1.5 cm×1.0 cm×0.3 cm.Histopathologic examination showed the tumour cells with rich in acidophilic cytoplasm,obvious nucleolus,mitotic phase in the dermis and fiber spaced in the middle were arranged in nests,infiltrated around the skin appendage and spread like Paget's disease in the surrounding epidermis.Immunohistochemistry study showed positive to EMA,CKpan,CKL,CK7,AR,CD15,CA153,Ki-67 and negative to CK14,CK17,CK20,CEA,Mamaglobin,GCDFP-15,CD34,D2-40.The scrotal sebaceous carcinoma was diagnosed.

参考文献/References:

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更新日期/Last Update: 2021-02-01