LIN Zhipeng,HUANG Xianqiong,LI Jinzhuo,et al.Progress of the Research on N-acetylcysteine in the Treatment of Skin Diseases[J].The Chinese Journal of Dermatovenereology,2021,(02):123-126.





Progress of the Research on N-acetylcysteine in the Treatment of Skin Diseases
陆军军医大学大坪医院皮肤科,重庆 400042
LIN ZhipengHUANG XianqiongLI JinzhuoZENG QianwenSUN Renshan
(Department of Dermatology,Daping Hospital,Army Medical University,Chongqing 400042,China)
N-乙酰半胱氨酸 皮肤病 治疗
N-acetylcysteine Skin diseases Treatment
R 751
N-acetylcysteine(NAC), which contains sulfhydryl(-SH)in the structure, is often used as a mucolytic drug.Studies have shown that NAC also has the functions of anti-oxidation, anti-inflammatory, and vasodilation improvement.In recent years, the unique action mechanism of NAC has been widely focused and shown good potential in the therapeutic application of skin diseases.This article systematically reviews the drug metabolism, pharmacological mechanism, therapeutic uses, and adverse reactions in NAC, in order to provide better options for the treatment of skin diseases.


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[基金项目] 国家自然科学基金(81571569)
[通信作者] 孙仁山,E-mail:pharsunr@126.com
更新日期/Last Update: 2021-02-01