[1]曾君,杨希川,张恋,等.褶皱部网状色素异常1例并家系调查[J].中国皮肤性病学杂志,2021,(01):73-60ff4d30-cb90-4967-8932-84a50364ca98/pdf.[doi:10.13735/j.cjdv.1001-7089.202003155]
 ZENG Jun,YANG Xichuan,ZHANG Lian,et al.A Case of Reticulate Pigmented Anomaly of the Flexures and Family Survey[J].The Chinese Journal of Dermatovenereology,2021,(01):73-60ff4d30-cb90-4967-8932-84a50364ca98/pdf.[doi:10.13735/j.cjdv.1001-7089.202003155]
点击复制

褶皱部网状色素异常1例并家系调查
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2021年01期
页码:
73-60ff4d30-cb90-4967-8932-84a50364ca98/pdf
栏目:
病例报告
出版日期:
2021-01-01

文章信息/Info

Title:
A Case of Reticulate Pigmented Anomaly of the Flexures and Family Survey
文章编号:
1001-7089(2021)01-0073-03
作者:
曾君杨希川张恋宋志强翟志芳
陆军军医大学第一附属医院皮肤科,重庆400038
Author(s):
ZENG JunYANG XichuanZHANG LianSONG ZhiqiangZHAI Zhifang
Department of Dermatology,the First Affiliated Hospital of Army Medical University,Chongqing 400038,China
关键词:
网状色素异常褶皱部 Dowling-Degos病 屈侧网状色素性皮病
Keywords:
Reticulate pigmented anomalythe flexures Dowling-Degos disease Reticulate pigmentation dermatosis of the flexures
分类号:
R 758.5
DOI:
10.13735/j.cjdv.1001-7089.202003155
文献标志码:
B
摘要:
患者女,52岁,胸腹部棕褐色丘疹斑片29年。既往体健,系统检查无异常。皮肤科情况:颈部、腋窝、乳房下等褶皱部密集分布棕褐色扁平丘疹或斑片,相互融合成网状。皮损组织病理示:表皮突呈鹿角状向下延长,真皮浅层血管周围少量淋巴细胞及组织细胞浸润,有散在噬色素细胞。家系调查显示家族4代中6人有类似皮损,男女各3人。诊断为褶皱部网状色素异常。
Abstract:
A 52-year-old female presented brown papules and macules on the breast and abdomen for 29 years. Previously she was in good condition and there was no positive symptoms in systemic examination. Physical examination showed small hyperpigmented flat papules or macules in a reticulate or confluent distribution,with a predilection for the flexural regions including neck,axillae,inframammary regions,and so on. Histopathological examination revealed the rete ridges were elongated downward in the shape of antlers. There were a few lymphocytes and histocytes infiltrated around the vessels of the superficial dermis,and scattered melanophages could also been observed. Pedigree survey showed there were 6 family members(3 males and 3 females)in 4 generations of the family had similar skin lesions. The diagnosis was made as reticulate pigmented anomaly of the flexures.

参考文献/References:

[1] Strausburg M,Linos K,Staser K,et al.Dowling-Degos disease co-presenting with Darier disease[J].Clin Exp Dermatol,2016,41(4):410-412.
[2] Ralser DJ,Basmanav FB,Tafazzoli A,et al.Mutations in gamma-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa[J].J Clin Invest,2017,127(4):1485-1490.
[3] Knuever J,Persa OD,Illerhaus A,et al.Mast cell activation in Dowling-Degos disease[J].Br J Dermatol,2019,181(6):1312-1314.
[4] Coco V,Guerriero C,Esposito I,et al.A familial case of Dowling-Degos disease on the vulva[J].Clin Exp Dermatol,2019,44(8):921-923.
[5] Agut-Busquet E,Gonzalez-Villanueva I,Romani DGJ,et al.Dowling-Degos disease and hidradenitis suppurativa epidemiological and clinical study of 15 patients and review of the literature[J].Acta Derm Venereol,2019,99(10):917-918.
[6] Mohanty P,Jain S,Mohapatra L,et al.Dowling-Degos disease-A novel presentation of an uncommon disease[J].Indian Dermatol Online J,2019,10(5):587-590.
[7] Linke M,Orouji A,Geraud C. Vesicular variant of Dowling-Degos disease[J].Br J Dermatol,2018,179(3):795-796.
[8] 冉立伟,兰东,贾红侠. Dowling-Degos 病 1 例[J].中国皮肤性病学杂志,2013,27(12):1272-1273.
[9] Wollina U,Hansel G,Lotti T,et al.Acanthosis nigricans-a two-sided coin:consider metabolic syndrome and malignancies[J].Open Access Maced J Med Sci,2019,7(18):3081-3084.
[10] Rundle CW,Ophaug S,Simpson EL. Acitretin therapy for Galli-Galli disease[J].JAAD Case Reports,2020,6(5):457-461.
[11] Yun JH,Kim JH,Choi JS,et al.Treatment of Dowling-Degos disease with fractional Er:YAG laser[J].J Cosmet Laser Ther,2013,15(6):336-339.

备注/Memo

备注/Memo:
[通信作者] 翟志芳,E-mail:zhaizf1004@163.com
更新日期/Last Update: 2021-01-10