[1]张颖,冯林,江阳,等.异色病样蕈样肉芽肿1例[J].中国皮肤性病学杂志,2020,(11):1310-1311.[doi:10.13735/j.cjdv.1001-7089.201912026]
 ZHANG Ying,FENG Lin,JIANG Yang,et al.A Case of Poikilodermatous Mycosis Fungoides[J].The Chinese Journal of Dermatovenereology,2020,(11):1310-1311.[doi:10.13735/j.cjdv.1001-7089.201912026]
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异色病样蕈样肉芽肿1例()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2020年11期
页码:
1310-1311
栏目:
病例报告
出版日期:
2020-11-01

文章信息/Info

Title:
A Case of Poikilodermatous Mycosis Fungoides
文章编号:
1001-7089(2020)11-1310-02
作者:
张颖冯林江阳郝进刁庆春卢阳
重庆市中医院(重庆市第一人民医院)皮肤科,重庆 400011
Author(s):
ZHANG YingFENG LinJIANG YangHAO JinDIAO QingchunLU Yang
Department of Dermatology,Chongqing Traditional Chinese Medicine Hospital,Chongqing First People's Hospital,Chongqing 400011,China
关键词:
蕈样肉芽肿异色病样
Keywords:
Mycosis fungoidespoikilodermatous
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201912026
文献标志码:
B
摘要:
患者男,24岁,躯干、四肢皮疹2年。皮肤科情况:躯干、四肢见弥漫分布暗红色至褐色斑片,其间可见色素沉着及点状色素减退,局部可见皮肤萎缩及毛细血管扩张,部分斑片上见糠秕状细碎脱屑。皮损组织病理示:角化过度,棘层轻度增生,真皮浅层淋巴细胞浸润,部分淋巴细胞核异型性,可见淋巴细胞亲表皮现象及Pautrier微脓肿样结构,部分区域胶原增生。免疫组织化学:CD3(+)、CD4(+)、CD5(+)、CD7(+)、CD8(-)、CD20(-)、CD30(-)、Ki-67(约5%+)。诊断:异色病样蕈样肉芽肿。
Abstract:
A 24-year-old male presented patches in trunk and limbs for 2 years.Physical examination showed diffuse dark red to brown patches on the trunk and limbs,with pigmentation,hypopigmentation,atrophy,telangiectasia and scaling.Histopathology showed hyperkeratosis,acanthosis of epidermis,infiltration of lymphocytes in papillary dermis and atypical lymphocytes,with Pautrier's microabscesses in the epidermis.Immunohistochemical investigation showed that CD3,CD4,CD5 and CD7 were positive,CD8,CD20 and CD30 negative,and Ki-67 about 5% positive.Poikilodermatous mycosis fungoides was finally diagnosed.

参考文献/References:

[1] Yildizhan I,Sanli H,Akay BN,et al.CD8+cytotoxic mycosis fungoides:a retrospective analysis of clinical features and follow-up results of 29 patients[J].Int J Dermatol,2020,59(1):127-133.
[2] 乌日勒,方凯,王家璧.异色病样蕈样肉芽肿2例[J].中国麻风皮肤病杂志,2011,27(1):57-59.
[3] Popadic S,Lekic B,Tanasilovic S,et al.Poikilodermatous mycosis fungoides with CD30-positive large cell transformation successfully treated by brentuximab vedotin[J].Dermatol Ther,2020,33(1):e13152.

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备注/Memo

备注/Memo:
[通信作者] 卢阳,E-mail:316684113@qq.com
更新日期/Last Update: 2020-11-16