[1]王芳,李博,陈雪,等.下肢软组织神经束膜瘤1例[J].中国皮肤性病学杂志,2020,(10):1186-1188.[doi:10.13735/j.cjdv.1001-7089.201910171]
 WANG Fang,LI Bo,CHEN Xue,et al.A Case of Soft Tissue Perineurioma on the Lower Leg[J].The Chinese Journal of Dermatovenereology,2020,(10):1186-1188.[doi:10.13735/j.cjdv.1001-7089.201910171]
点击复制

下肢软组织神经束膜瘤1例()
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2020年10期
页码:
1186-1188
栏目:
病例报告
出版日期:
2020-10-01

文章信息/Info

Title:
A Case of Soft Tissue Perineurioma on the Lower Leg
文章编号:
1001-7089(2020)10-1186-03
作者:
王芳李博陈雪张建中金江
北京大学人民医院皮肤科,北京 100044
Author(s):
WANG FangLI BoCHEN XueZHANG JianzhongJIN Jiang
Peking University People's Hospital,Beijing 100044,China
关键词:
神经束膜瘤 EMA CD34 Vimentin
Keywords:
Perineurioma EMA CD34 Vimentin
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201910171
文献标志码:
B
摘要:
患者女,60岁,右小腿皮肤肿物3年。皮损组织病理示:真皮内肿瘤组织结节状,由梭形细胞排列呈编席状,伴有黏液变性。免疫组织化学示:EMA(+),CD34(+),Vimentin(+),Ki-67(5%+)。诊断:软组织神经束膜瘤。该肿瘤相对罕见,其病理及免疫组织化学具有特征性。
Abstract:
A 60-year-old female patient was admitted to hospital with a mass on the right lower leg for 3 years.Histopathology showed the nodular tissue in dermis was composed of spindle cells which were arranged in a braided shape accompanied by mucous degeneration.Immunohistochemistry showed EMA(+),CD34(+),vimentin(+)and 5% positive of Ki-67.Soft tissue perineurioma is rare.Histopathology and immunohistochemistry are helpful for the diagnosis.

参考文献/References:

[1] Pina-Oviedo S,Ortiz-Hidalgo C.The normal and neoplastic perineurium:a review[J].Adv Anat Pathol,2008,15(3):147-164.
[2] Mauermann ML,Amrami KK,Kuntz NL,et al.Longitudinal study of intraneural perineurioma-a benign,focal hypertrophic neuropathy of youth[J].Brain,2009,132(Pt8):2265-2276.
[3] Jazayeri MA,Robinson JH,Legolvan DP.Intraneural perineurioma involving the median nerve[J].Plast Reconstr Surg,2000,105(6):2089-2091.
[4] Kurihara J,Yokoo S,Ichikawa M,et al.Intraosseous intraneural perineurioma derived from the inferior alveolar nerve with an abnormality of chromosome 22 and expression of the BCR-ABL fusion gene:report of a case and review of recent literature[J].World J Surg Oncol,2018,16(1):189.
[5] Mott RT,Goodman BK,Burchette JL,et al.Loss of chromosome 13 in a case of soft tissue perineurioma[J].Clin Neuropathol,2005,24(2):69-76.

备注/Memo

备注/Memo:
[通信作者] 金江,E-mail:jiang_jin@yahoo.com
更新日期/Last Update: 2020-10-15