[1]付金玲,余勋.儿童手足口病后甲脱落117例的病因学分析[J].中国皮肤性病学杂志,2020,(10):1152-1154.[doi:10.13735/j.cjdv.1001-7089.201912003]
 FU Jinling,YU Xun.Etiology of Onychomadesis Related with Hand Foot and Mouth Disease in 117 Children[J].The Chinese Journal of Dermatovenereology,2020,(10):1152-1154.[doi:10.13735/j.cjdv.1001-7089.201912003]
点击复制

儿童手足口病后甲脱落117例的病因学分析()
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2020年10期
页码:
1152-1154
栏目:
临床经验
出版日期:
2020-10-01

文章信息/Info

Title:
Etiology of Onychomadesis Related with Hand Foot and Mouth Disease in 117 Children
文章编号:
1001-7089(2020)10-1152-03
作者:
付金玲1余勋2
1.东莞市妇幼保健院皮肤科,广东 东莞 523000; 2.东莞市妇幼保健院检验科,广东 东莞 523000
Author(s):
FU Jinling1YU Xun2
1.Department of Dermatology,Dongguan Maternal and Child Health Care Hospital,Dongguan 523000,China; 2.Department of Laboratory,Dongguan Maternal and Child Health Hospital,Dongguan 523000,China
关键词:
手足口病 甲脱落 肠道病毒 微量元素
Keywords:
Hand foot and mouth disease Onychoptosis Enterovirus Trace elements
分类号:
R 725.1; R 758.72
DOI:
10.13735/j.cjdv.1001-7089.201912003
文献标志码:
B
摘要:
目的 探讨儿童手足口病后甲脱落与病毒类型及患者体内血微量元素水平的相关性。方法 117例儿童手足口病后甲脱落患者均为本院皮肤科门诊病人,肠道病毒检测情况采取回顾性分析法并同时对其行血微量元素检测。结果 117例儿童手足口病后甲脱落患者病毒检测结果显示,肠道病毒感染阳性例数为91例,总阳性率为77.78%。其中肠道病毒71型(EV71)阳性例数为2例,占构成比的2.20%; 柯萨奇病毒A16型(CoxA16)阳性例数为3例,占构成比的3.30%,其他EV阳性例数为86例,占构成比的94.51%。117例儿童手足口病后脱甲患者血微量元素检测结果显示,脱甲病患者体内锌、钙、镁、铁、铜水平与同期健康儿童比较,差异无统计学意义。结论 引起儿童手足口病后脱甲发生的主要病原为除EV71及CoxA16以外的其他肠道病毒。脱甲的发生与病毒感染类型有关,与患者体内血微量元素水平无关。
Abstract:
Objective To investigate the correlation between onychomadesis related with hand foot and mouth disease(HFMD)of children and virus type and serum trace element.Methods One hundred and seventeen cases of onychomadesis related with HFMD were all outpatients of dermatology department of our hospital.A retrospective survey was conducted among viral types.The serum trace elements were detected simultaneously.Results The positive number of enterovirus infection were 91 among the 117 onychomadesis related with HFMD cases,account for 77.78%.In 91 positive cases,the positive constituent ratio were:EV positive only 2.20%(2/91),CoxA16 positive only 3.30%(3/91)and other EV positive 94.51%(86/91).The levels of zinc,calcium,magnesium,iron and copper in the onychomadesis related with HFMD had no statistical significance compared with those in healthy children.Conclusion The onychomadesis related with HFMD in children was related to the other enteroviruses,but not EV71 and CoxA16.The result demonstrated a correlation of viral types and it was not associated with serum trace element.

参考文献/References:

[1] Mao QY,Wang Y,Bian L,et al.EV71 vaccine,a new tool to control outbreaks of hand,foot and mouth disease(HFMD)[J].Expert Rev Vaccines,2016,15(5):599-606.
[2] 李清,陆原,翁翊,等.手足口病相关性Beau线/甲脱落[J].实用皮肤病学杂志,2014,7(5):324-326.
[3] Hardin J,Haber RM.Onychomadesis:literature review[J].Br J Dermatol,2015,172(3):592-596.
[4] 汤建萍,胡梦叶,韦祝.儿童手足口病后脱甲病的临床特点[J].中国当代儿科杂志,2014,16(12):1275-1276.
[5] Navarro Moreno E,Almagro López D,Jaldo Jiménez R.et al.Outbreak of hand,foot and mouth disease with onychomadesis caused by Coxsackie virus A16 in Granada[J].An Pediatr(Barc),2015,82(4):235-241.
[6] 邓慧玲,张玉凤,马超峰,等.以大疱样皮疹为特征的手足口病病原学及临床特点分析[J].中华儿科杂志,2015,53(8):616-620.
[7] 王继辉,朱慧玲.手足口病相关甲损害60例临床分析[J].广东医学,2018,39(2):247-250.
[8] 张晓俐,任一帆,陈芳,等.69例手足口病临床特点及合并甲损伤相关因素分析[J].中国卫生检验杂志,2017,27(2):250-255.

相似文献/References:

[1]吴小莉,李钟洙,张召力,等.成人手足口病误诊为多形红斑、水痘2例[J].中国皮肤性病学杂志,2015,(05):542.[doi:10.13735/j.cjdv.1001-7089.201409115]
 WU Xiao li,LI Zhong zhu,ZHANG Zhao li,et al.Two Cases of Adult Hand,Foot and Mouth Disease Misdiagnosed as Erythema Multiforme and Chicken Pox[J].The Chinese Journal of Dermatovenereology,2015,(10):542.[doi:10.13735/j.cjdv.1001-7089.201409115]
[2]赵金仙,杨汝松,张红强,等.2011-2014年玉溪市中小学生手足口病流行特征分析[J].中国皮肤性病学杂志,2016,(08):836.[doi:10.13735/j.cjdv.1001-7089.201505099]
 ZHAO Jin-xian,YANG Ru-song,ZHANG Hong-qiang,et al.The Epidemiological Analysis of Hand-foot-and-mouth Disease of Students in Yuxi, 2011-2014[J].The Chinese Journal of Dermatovenereology,2016,(10):836.[doi:10.13735/j.cjdv.1001-7089.201505099]
[3]周兴雯*,冉玉平,康道现,等.手足口病后出现甲分离和甲横沟3例报道及文献复习[J].中国皮肤性病学杂志,2014,(04):427.
 ZHOU Xing wen,RAN Yu ping,KANG Dao xian,et al.Onycholysis andBeaus Lines after Handfootmouth Disease:3 Case Reports and Literature Review[J].The Chinese Journal of Dermatovenereology,2014,(10):427.

更新日期/Last Update: 2020-10-15