[1]师小萌,邢倩,李领娥,等.共聚焦显微镜在常见结缔组织病中的图像特征分析[J].中国皮肤性病学杂志,2020,(06):644-649.[doi:10.13735/j.cjdv.1001-7089.201906042]
 SHI Xiaomeng,XING Qian,LI Ling'e,et al.Image Features of Connective Tissue Diseases Using Confocal Laser Scanning Microscope[J].The Chinese Journal of Dermatovenereology,2020,(06):644-649.[doi:10.13735/j.cjdv.1001-7089.201906042]
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共聚焦显微镜在常见结缔组织病中的图像特征分析
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2020年06期
页码:
644-649
栏目:
临床经验
出版日期:
2020-06-01

文章信息/Info

Title:
Image Features of Connective Tissue Diseases Using Confocal Laser Scanning Microscope
文章编号:
1001-7089(2020)06-0644-06
作者:
师小萌邢倩李领娥张金芳白艳秋张立欣边莉陈潍吕培李佩赛
石家庄市中医院皮肤科,河北 石家庄 050081
Author(s):
SHI XiaomengXING QianLI Ling'eZHANG JinfangBAI YanqiuZHANG LixinBIAN LiCHEN WeiLYU PeiLI Peisai
(Department of Dermatology,Shijiazhuang Traditional Chinese Medicine Hospital,Shijiazhuang050081,China)
关键词:
结缔组织病 共聚焦显微镜(RCM) 组织病理 图像特征 分析
Keywords:
Connective tissue diseases RCM(rellectance confocal microscopy) Histopathological Image features Analyse
分类号:
R 593.2
DOI:
10.13735/j.cjdv.1001-7089.201906042
文献标志码:
B
摘要:
目的 分析常见结缔组织病(CTD)的共聚焦显微镜(RCM)图像特征。方法 回顾性分析32例常见CTD的RCM图像、组织病理资料,并进行对比分析。结果 在RCM检查中,红斑狼疮(LE)、皮肌炎(DM)、硬化性苔藓均表现为界面皮炎,真皮浅层嗜色素细胞及色素颗粒,其中毛囊角栓、真皮浅层血管扩张充血在红斑狼疮及硬化性苔藓中常见。在硬皮病中浅层胶原折光略增强,在硬化性苔藓中胶原折光显著增强,走向僵硬或呈放射状排列,也可呈棉絮状,或境界模糊呈片状无结构影,失去原有纵横交错的排列方式。结论 RCM在常见CTD中的图像特征与组织病理改变颇为吻合,可以作为临床筛查CTD的有效无创检查方法,并可在治疗随访当中观察皮疹改善程度。
Abstract:
Objective To analyze imaging features of common connective tissue diseases(CTD)using the rellectance confocal microscopy(RCM).Methods The RCM and histopathological data of 32 cases common CTD were retrospectively analyzed and compared.Results On RCM examination,lupus erythematosus(LE),dermatomyositis(DM)and lichen sclerosus were all manifested as interfacial dermatitis,superficial dermal pigmentophils and pigmentation granules,among which hair follicle keratosis and superficial dermal vasodilation and hyperemia were common in LE and lichen sclerosus.Superficial collagen refraction was increased slightly in scleroderma,and markedly increased in lichen sclerosus,which tended to be stiff or radial arranged,or in the shape of cotton flocculence,or blurred without structure,losing the original crisscross pattern.Conclusion The imaging features of RCM in common CTD are consistent with histopathological changes.Therefore,it can be used as an effective non-invasive method for clinical screening of CTD,and to observe the improvement of skin rash during treatment and follow-up.

参考文献/References:

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备注/Memo

备注/Memo:
[网络首发时间] 2020-4-15 14:15
[网络首发地址] http://kns.cnki.net/kcms/detail/61.1197.r.20200414.1319.006.html
更新日期/Last Update: 2020-06-05