参考文献/References:
[1] 沈如飞,曾繁典,师少军.硫唑嘌呤的药理作用和临床应用研究进展[J].中国药师,2013,16(9):1409-1412.
[2] Meyer V,Beissert S.Azathioprine in the treatment of autoimmune blistering diseases[J].Dermatol Clin,2011,29(4):545-554.
[3] Wang L,Weinshilboum R.Thiopurine S-methyltransferase pharmacogenetics:insights,challenges and future directions[J].Oncogene,2006,25(11):1629-1638.
[4] Karran P.Thiopurines,DNA damage,DNA repair and therapy-related cancer[J].Br Med Bull,2006,(79-80):153-170.
[5] Relling MV,GardnerEE,Sandborn WJ,et al.Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing:2013 update.[J].Clinical Pharmacol Ther,2013,93(4):324-325.
[6] 刘跃平,徐含青,杨翔,等.TPMT基因型在中国人群中的分布[J].临床检验杂志,2015,33(9):711-714.
[7] Schmiegelow K,Nielsen SN,Frandsen TL,et al.Mercaptopurine/ Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia:clinical facts and fiction [J].J Pediatr Hematol Oncol,2014,36(7):503-517.
[8] 陈潇潇,沈树红.巯嘌呤的药物基因组学研究进展[J].中国当代儿科杂志,2017,19(9):1027-1033.
[9] Liang DC,Yang CP,Liu HC,et al.NUDT15 gene polymorphism related to mercaptopurine intolerance in Taiwan Chinese children with acute lymphoblastic leukemia[J].Pharmacogenomics J,2016,16(6):536-539.
[10] Chiengthong K,Ittiwut C,Muensri S,et al.NUDT15 c.415C>T increases risk of 6-mercaptopurine induced myelosuppression during maintenance therapy in children with acute lymphoblastic leukemia[J].Haematologica,2016,101(1):e24-e26.
[11] Yang SK,Hong M,Baek J,et al.A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia[J].Nat Genet,2014,46(9):1017-1020.
[12] Valerie NC,Hagenkort A,Page BD,et al.NUDT15 hydrolyzes 6-thio-deoxyGTP to mediate the anticancer efficacy of 6-thioguanine[J].Cancer Res,2016,76(18):5501-5511.
[13] Singh M,Bhatia P,Khera S,et al.Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia[J].Leuk Res,2017,62:17-22.
[14] Moriyama T,Nishii R,Perez-Andreu V,et al.NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity[J].Nat Genet,2016,48(4):367-373.
[15] Neurath MF,Kiesslich R,Fischer C,et al.6-thioguanosine diphosphate and triphosphate levels in red blood cells and response to azathioprine therapy in Crohn's disease[J].Clin Gastroenterol Hepatol,2005,3(10):1007-1014.
[16] Nishii R,Moriyama T,Janke LJ,et al.Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and anti-leukemic efficacy[J].Blood,2018,131(22):2466-2474.
[17] Wong FC,Leung AW,Kwok JS,et al.NUDT15 variant and thiopurine-induced leukopenia in Hong Kong[J].Hong Kong Med J,2016,22(2):185-187.
[18] Yan W,Zhou YH,Wang L,et al.NUDT15 polymorphism and severe azathioprine-induced myelosuppression in a Chinese man with pemphigus vulgaris[J].Br J Dermatol,2018,178(1):e40-e41.
[19] Shih YC,Zou YR,Wang B,et al.Azathioprine-induced myelosuppression intwo pemphigus vulgaris patients with homozygous polymorphism of NUDT15[J].J Dermatol,2019,46(2):e59-e61.
[20] Hertl M,Jedlickova H,Karpati S,et al.Pemphigus.S2 Guideline for diagnosis and treatment-guided By the European Dermatology Forum(EDF)in cooperation with the European Academy of Dermatology and Venereology(EADV)[J].J Eur Acad Dermatol Venereol,2015,29(3):405-414.
[21] Committee for guidelines for the management of pemphigus disease,Amagai M,Tanikawa A,et al.Japanese guidelines for the management of pemphigus[J].J Dermatol, 2014,41(6):471-486.
[22] 张弦,许人超,元慧杰,等.寻常型天疱疮63例疗效分析[J].江苏医药,2016,42(1):97-99.
[23] Chams-Davatchi C,Esmaili N,Daneshpazhooh M,et al.Randomized controlled open-label trial of four treatment regimens for pemphigus vulgaris[J].J Am Acad Dermatol,2007,57(4):622-628.
[24] Martin LK,Werth V,Villanueva E,et al.Interventions for pemphigus vulgaris and pemphigus foliaceus[J].Cochrane Database Syst Rev,2009,(1):CD006263.
[25] Lee YJ,Hwang EH,Park JH,et al.NUDT15 variant is the most common variant associated with thiopurine-induced early leukopenia and alopecia in Korean pediatric patients with Crohn's disease[J].Eur J Gastroenterol Hepatol,2016,28(4):475-478.
相似文献/References:
[1]蒋冠,黄小凤,庞雁宇,等.夫西地酸联合糠酸莫米松治疗慢性家族性良性天疱疮22例临床观察[J].中国皮肤性病学杂志,2017,(11):1281.[doi:10.13735/j.cjdv.1001-7089.201701001]
JIANG Guan,HUANG Xiao-feng,PANG Yan-yu,et al.Clinical Observation of Fusidic Acid Cream Therapy Combined with Mometasone Furoate Cream for Hailey-Hailey Disease[J].The Chinese Journal of Dermatovenereology,2017,(05):1281.[doi:10.13735/j.cjdv.1001-7089.201701001]
[2]刘琼,许贵霞,张思平.天疱疮患者感染危险因素分析[J].中国皮肤性病学杂志,2019,(07):788.[doi:10.13735/j.cjdv.1001-7089.201809116]
LIU Qiong,XU Guixia,ZHANG Siping.Risk Factors for Infection in Patients with Pemphigus[J].The Chinese Journal of Dermatovenereology,2019,(05):788.[doi:10.13735/j.cjdv.1001-7089.201809116]
[3]胡凤侠,梁俊琴,毛丽旦,等.Neumann型增殖型天疱疮7例临床分析[J].中国皮肤性病学杂志,2021,(01):48.[doi:10.13735/j.cjdv.1001-7089.202005183]
HU Fengxia,LIANG Junqin,MAO Lidan,et al.Clinical Analysis of 7 Cases of the Neumann Type of Pemphigus Vegetans[J].The Chinese Journal of Dermatovenereology,2021,(05):48.[doi:10.13735/j.cjdv.1001-7089.202005183]
[4]李秀秀,吴楠,杜文辉,等.天疱疮患者273例组织病理和免疫病理分析[J].中国皮肤性病学杂志,2021,(01):110.[doi:10.13735/j.cjdv.1001-7089.202006070]
LI Xiuxiu,WU Nan,DU Wenhui,et al.Study on Histopathological and Immunopathological Findings in 273 Cases of Patients with Pemphigus[J].The Chinese Journal of Dermatovenereology,2021,(05):110.[doi:10.13735/j.cjdv.1001-7089.202006070]