[1]闫慧敏,姜薇.成人初发的泛发性湿疹合并纵隔原发性弥漫性大B细胞淋巴瘤1例[J].中国皮肤性病学杂志,2019,(10):1174-1176.[doi:10.13735/j.cjdv.1001-7089.201812134]
 YAN Huimin,JIANG Wei.A Case of Adult-onset Generalized Eczema with Primary Mediastinal Diffuse Large B-cell Lymphoma[J].The Chinese Journal of Dermatovenereology,2019,(10):1174-1176.[doi:10.13735/j.cjdv.1001-7089.201812134]
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成人初发的泛发性湿疹合并纵隔原发性弥漫性大B细胞淋巴瘤1例
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年10期
页码:
1174-1176
栏目:
病例报告
出版日期:
2019-09-13

文章信息/Info

Title:
A Case of Adult-onset Generalized Eczema with Primary Mediastinal Diffuse Large B-cell Lymphoma
文章编号:
1001-7089(2019)10-1174-03
作者:
闫慧敏1姜薇2
1.天津市第一中心医院皮肤科,天津 300192; 2.北京大学第三医院皮肤科,北京 100191
Author(s):
YAN Huimin1JIANG Wei2
(1.Department of Dermatology,Tianjin First Center Hospital,Tianjin 300192,China; 2.Department of Dermatology,Peking University Third Hospital,Beijing 100191,China)
关键词:
湿疹 纵隔原发性弥漫性大B细胞淋巴瘤 非霍奇金淋巴瘤
Keywords:
Eczema Primary mediastinal large B-cell lymphoma Non-Hodgkin lymphoma
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201812134
文献标志码:
B
摘要:
患者男,36岁,泛发性湿疹伴瘙痒4个月。患者全身泛发红褐色、棕色粟粒至黄豆大斑疹、斑丘疹,部分融合成片状,其上可见点状结痂及细碎鳞屑,躯干可见毛细血管扩张。左颈部、双锁骨上多发肿大淋巴结。纵隔肿物经皮穿刺活检示:非霍奇金淋巴瘤,弥漫性大B细胞型。免疫组织化学:CD20(+)、LCA(+)、Ki-67(40%~50%+)、CD30(+)、CD99(+)。诊断:纵隔原发性弥漫性大B细胞淋巴瘤。
Abstract:
A 36-year-old male presented a four-month history of generalized eczema and pruritus.The whole body was covered with reddish-brown or brown maculopapules,sized millet to soybean,with dotted scabs and fine scales.Some of maculopapules merged together.Telangiectasias were present on the trunk.Multiple enlarged lymph nodes were found in the left neck and both supraclavicular areas.A percutaneous biopsy of a mediastinal mass showed non-hodgkin lymphoma with diffuse large B cells.Immunohistochemistry showed CD20(+),LCA(+),Ki-67(40%~50%+),CD30(+),and CD99(+).The diagnosis of primary mediastinal diffuse large B-cell lymphoma was made.

参考文献/References:

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[5] Callen JP,Bernardi DM,Clark RA,et al.Adult-onset recalcitrant eczema:a marker of noncutaneous lymphoma or leukemia[J].J Am Acad Dermatol,2000,43(2 Pt 1):207-210.
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备注/Memo

备注/Memo:
[作者单位] 1.天津市第一中心医院皮肤科,天津 300192; 2.北京大学第三医院皮肤科,北京 100191
[通讯作者] 姜薇,E-mail:jiangwei7366@163.com
更新日期/Last Update: 2019-09-12