[1]白瑶,石春蕊,刘昱彤,等.二期梅毒误诊为荨麻疹性血管炎1例[J].中国皮肤性病学杂志,2019,(07):849-850.[doi:10.13735/j.cjdv.1001-7089.201804003]
 BAI Yao,SHI Chunrui,LIU Yutong,et al.A Case of Secondary Syphilis Misdiagnosed as Urticarial Vasculitis[J].The Chinese Journal of Dermatovenereology,2019,(07):849-850.[doi:10.13735/j.cjdv.1001-7089.201804003]
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二期梅毒误诊为荨麻疹性血管炎1例
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年07期
页码:
849-850
栏目:
误诊教训
出版日期:
2019-06-16

文章信息/Info

Title:
A Case of Secondary Syphilis Misdiagnosed as Urticarial Vasculitis
文章编号:
1001-7089(2019)07-0849-02
作者:
白瑶1石春蕊1刘昱彤1 武奕1白瑛2骆志成2
1.兰州大学第一医院皮肤科,甘肃 兰州 730000; 2.兰州大学第二医院皮肤科,甘肃 兰州 730000
Author(s):
BAI Yao1SHI Chunrui1LIU Yutong1WU Yi1BAI Ying2LUO Zhicheng2
(1.Department of Dermatology,the First Clinical Medicine of Lanzhou University,Lanzhou 730000,China; 2.Department of Dermatology,the Second Clinical Medicine of Lanzhou University,Lanzhou 730000,China)
关键词:
二期梅毒 荨麻疹性血管炎 误诊
Keywords:
Secondary syphilis Urticarial vasculitis Misdiagnosis
分类号:
R 758.24
DOI:
10.13735/j.cjdv.1001-7089.201804003
文献标志码:
B
摘要:
患者女,20岁,全身出现水肿性红斑伴痒10 d,加重4 d。拟诊“荨麻疹性血管炎”,行梅毒血清学检查:TPPA(+),RPR(+)1:32; 皮损组织病理示:角化过度,上皮突存在,棘层肥厚,基底膜完整,真皮浅层及小血管周围可见淋巴细胞及浆细胞浸润。诊断:二期梅毒。给予苄星青霉素240万U驱梅治疗,连用3周。患者皮损已消退,目前在随访中。
Abstract:
A 20-year-old female presented with generalized edematous erythema and pruritus for 10 days,which was aggravated for four days.Primary diagnosis was urticarial vasculitis.Syphilis serology revealed TPPA(+)and RPR(+)1:32.Histological examination revealed hyperkeratosis,presence of epidermal ridge,acanthosis,basement membrane intactness,lymphocytes and phlogocytes infiltratration in superficial dermis and perivascular space.The diagnosis of secondary syphilis was made.A dose of 2.4 million U benzathine benzylpenicillin was administered once a week for consecutive three weeks,and the lesions disappeared.Currently,the patient is being followed up.

参考文献/References:

[1] 赵辨.中国临床皮肤病学[M].南京:江苏科学技术出版社,2010:1787.
[2] 张彦秀.二期梅毒误诊为皮炎1例[J].中国皮肤性病学杂志,2015,29(5):544.
[3] 付锐,扬钧.二期梅毒误诊为银屑病2例[J].中国皮肤性病学杂志,2017,31(1):104-105.
[4] Guardoli D,Reggiani C,Ciardo S,et al.New imaging tools for an old disease:Secondary syphilis[J].Australas Dermatol,2017,58(4):277-279.

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备注/Memo

备注/Memo:
[作者单位] 1.兰州大学第一医院皮肤科,甘肃 兰州 730000; 2.兰州大学第二医院皮肤科,甘肃 兰州 730000
[通讯作者] 白瑛,E-mail:baiyinglz@163.com
[Corresponding author] BAI Ying,E-mail:baiyinglz@163.com
更新日期/Last Update: 2019-06-15