[1]吴先伟,邓秀娥,汪舰笛.Tavarborole治疗甲真菌病的疗效和安全性[J].中国皮肤性病学杂志,2019,(06):721-723.[doi:10.13735/j.cjdv.1001-7089.201805138]
 WU Xianwei,DENG Xiue,WANG Jiandi.Efficacy and Safety of Tavaborole in the Treatment of Onychomycosis[J].The Chinese Journal of Dermatovenereology,2019,(06):721-723.[doi:10.13735/j.cjdv.1001-7089.201805138]
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Tavarborole治疗甲真菌病的疗效和安全性
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年06期
页码:
721-723
栏目:
继续医学教育
出版日期:
2019-05-16

文章信息/Info

Title:
Efficacy and Safety of Tavaborole in the Treatment of Onychomycosis
文章编号:
1001-7089(2019)06-0721-03
作者:
吴先伟邓秀娥汪舰笛
甘肃省人民医院皮肤科,甘肃 兰州 730000
Author(s):
WU XianweiDENG XiueWANG Jiandi
(Department of Dermatology,Gansu Provincial Hospital,Lanzhou 730000,China)
关键词:
Tavaborole 甲真菌病 疗效 安全性
Keywords:
Tavaborole Onychomycosis Efficacy Safety
分类号:
R 756.4
DOI:
10.13735/j.cjdv.1001-7089.201805138
文献标志码:
A
摘要:
Tavarborole是一种氧硼戊环类抗真菌药,特异性地抑制亮氨酰转移核糖核酸合成酶抑制真菌蛋白的合成,用于治疗甲真菌病。现对其药效学、药代动力学、临床疗效和安全性等内容进行综述。
Abstract:
Tavaborole is an oxaborole antifungal drug.The medication binds at the enzyme-editing site of cytoplasmic leucyl-tRNA synthetase and prevents fungal protein synthase.In this article,the pharmacodynamics,pharmacokinetics,clinical efficacy,and safety profile of tavaborole has been reviewed.

参考文献/References:


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[12] Elewski BE,Aly R,Baldwin SL,et al.Efficacy and safety of tavaborole topical solution,5%,a novel boron-based antifungal agent,for the treatment of toenail onychomycosis:Results from 2 randomized phase-III studies[J].J Am Acad Dermatol,2015,73(1):62-69.
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备注/Memo

备注/Memo:
[基金项目] 甘肃省自然科学基金(18JR3RA056)
[作者单位] 甘肃省人民医院皮肤科,甘肃 兰州 730000
更新日期/Last Update: 2019-05-16