[1]王柳苑,柯吴坚,张晓辉,等.硬化性脂膜炎17例临床及组织病理特点[J].中国皮肤性病学杂志,2019,(06):671-673.[doi:10.13735/j.cjdv.1001-7089.201807095]
 WANG Liuyuan,KE Wujian,ZHANG Xiaohui,et al.Clinical and Histopathological Features of 17 Cases of Sclerosing Panniculitis[J].The Chinese Journal of Dermatovenereology,2019,(06):671-673.[doi:10.13735/j.cjdv.1001-7089.201807095]
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硬化性脂膜炎17例临床及组织病理特点
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年06期
页码:
671-673
栏目:
临床经验
出版日期:
2019-05-16

文章信息/Info

Title:
Clinical and Histopathological Features of 17 Cases of Sclerosing Panniculitis
文章编号:
1001-7089(2019)06-0671-03
作者:
王柳苑柯吴坚张晓辉陈征宇潘慧清杨立刚
南方医科大学皮肤病医院,广东 广州 510091
Author(s):
WANG LiuyuanKE WujianZHANG XiaohuiCHEN ZhengyuPAN HuiqingYANG Ligang
(Dermatology Hospital of Southern Medical University,Guangzhou 510091,China)
关键词:
硬化性脂膜炎 脂肪皮肤硬化症 组织病理 治疗
Keywords:
Sclerosing panniculitis Lipodermatosclerosis Pathology Therapy
分类号:
R 758.6
DOI:
10.13735/j.cjdv.1001-7089.201807095
文献标志码:
B
摘要:
目的 分析硬化性脂膜炎的临床特征及病理学特点,提高对本病的认识和诊断。方法 对17例确诊的硬化性脂膜炎患者的临床表现、组织病理、诊断及治疗进行回顾性分析。结果 本组17例患者中男5例,女12例,平均年龄59.29岁,平均病程14个月。皮疹主要累及小腿中下1/3处,临床表现为皮下红色斑块、结节或萎缩性硬化性斑块,可有色素沉着,伴疼痛,部分患者患侧小腿形成“倒置香槟瓶状”外观。所有患者经过病理确诊,病理特征为皮下脂肪间隔胶原增粗、硬化,脂肪小叶微囊形成及脂膜性脂肪坏死。结论 硬化性脂膜炎临床容易误诊,确诊主要依靠临床及病理,临床治疗较困难。
Abstract:
Objective To analyze the clinical and pathological features of sclerosing panniculitis and to improve the knowledge and diagnosis of sclerosing panniculitis.Methods The clinical manifestations,histopathology,diagnosis and treatment of 17 patients with sclerosing panniculitis were retrospectively analyzed.Results There were 17 patients in this group,including 5 males and 12 females,with an average age of 59.29 years,with an average course of 14 months.The rash mainly involved the lower 1/3 of the lower leg.The clinical manifestations were red patches,nodules or atrophic sclerosing plaques in the subcutaneous with pigmentation and pain.Some patients suffered from the “inverted champagne bottle” appearance.All patients were pathologically diagnosed,characterized by subcutaneous fat septal collagen thickened and sclerotic,fatty lobular microcapsule formation and lipomembranous fat necrosis.Conclusion Sclerosing panniculitis is easily misdiagnosed.Diagnosis relies mainly on clinical features and pathology,and clinical treatment is difficult.

参考文献/References:


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备注/Memo

备注/Memo:
[作者单位] 南方医科大学皮肤病医院,广东 广州 510091
[通讯作者] 杨立刚,E-mail:yanglg3@hotmail.com
更新日期/Last Update: 2019-05-16