[1]雷东春,张守民,李振鲁,等.结节性硬化症在共聚焦激光扫描显微镜下的影像特征初探[J].中国皮肤性病学杂志,2019,(06):657-660.[doi:10.13735/j.cjdv.1001-7089.201806022]
 LEI Dongchun,ZHANG Shoumin,LI Zhenlu,et al.Image Features of Tuberous Sclerosis in Confocal Laser Scanning Microscopy[J].The Chinese Journal of Dermatovenereology,2019,(06):657-660.[doi:10.13735/j.cjdv.1001-7089.201806022]
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结节性硬化症在共聚焦激光扫描显微镜下的影像特征初探
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年06期
页码:
657-660
栏目:
临床经验
出版日期:
2019-05-16

文章信息/Info

Title:
Image Features of Tuberous Sclerosis in Confocal Laser Scanning Microscopy
文章编号:
1001-7089(2019)06-0657-04
作者:
雷东春张守民李振鲁王建波李建国袁星海王豫平王国芳
河南省人民医院皮肤科,河南 郑州 450003
Author(s):
LEI DongchunZHANG ShouminLI ZhenluWANG JianboLI JianguoYUAN XinghaiWANG YupingWANG Guofang
(Department of Dermatology,Henan Provincial People's Hospital,Zhengzhou 450003,China)
关键词:
结节性硬化症 共聚焦激光扫描显微镜 影像特征
Keywords:
Tuberous sclerosis Confocal laser scanning microscope Image features
分类号:
R 596.1
DOI:
10.13735/j.cjdv.1001-7089.201806022
文献标志码:
B
摘要:
目的 探讨结节性硬化症在体共聚焦激光扫描显微镜(CLSM)的影像学特征。方法 选取皮肤科7例结节性硬化症患者,经CLSM检查后进行组织病理确诊,分析其影像学特征。结果 与周围正常皮肤相比,结节性硬化症在CLSM下可观察到毛囊周围的色素环围绕毛囊呈条状环形同心排列,伴基底层色素增多,真皮浅、中层及毛囊周围胶原折光较高,且毛囊周围胶原呈现网格状改变。结论 结节性硬化症的CLSM图像有明显的特征性,且与其常规组织病理特征具有很好的一致性,可为该病的临床诊断和鉴别诊断提供有效的帮助。
Abstract:
Objective To explore the image features of tuberous sclerosis by confocal laser scanning microscope(CLSM).Methods Seven patients with tuberous sclerosis were selected from dermatology department and were detected by CLSM.At the same time,the image features of tuberous sclerosis were analyzed after the diagnosis of pathological tissues.Results Compared with the surrounding normal skin,the images of tuberous sclerosis in CLSM can be observed that the pigment ring around the hair follicle presented concentric arrangement,pigment in the base increased,collagen refractive index in the shallow and middle dermis and around the hair follicle was higher,which presented grid change around the hair follicles.Conclusion The images of tuberous sclerosis in CLSM have obvious characteristic and are consistency with histopathologic features.It can provide effective help for the clinical diagnosis and differential diagnosis of tuberous sclerosis.

参考文献/References:


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备注/Memo

备注/Memo:
[作者单位] 河南省人民医院皮肤科,河南 郑州 450003
[通讯作者] 李振鲁,E-mail:1419480293@qq.com
更新日期/Last Update: 2019-05-16