[1]徐萍,赵小兴.红花逍遥片联合氨甲环酸片和对苯二酚乳膏治疗肝郁气滞型黄褐斑的疗效观察[J].中国皮肤性病学杂志,2019,(05):620-622.[doi:10.13735/j.cjdv.1001-7089.201803159]
 XU Ping,ZHAO Xiaoxing.Efficacy Observation of Honghua Xiaoyao Tablet Combined with Tranexamic Acid Tablet and Hydroquinone Cream for liver-qi Stagnation Type Melasma[J].The Chinese Journal of Dermatovenereology,2019,(05):620-622.[doi:10.13735/j.cjdv.1001-7089.201803159]
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红花逍遥片联合氨甲环酸片和对苯二酚乳膏治疗肝郁气滞型黄褐斑的疗效观察
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2019年05期
页码:
620-622
栏目:
药物与临床
出版日期:
2019-04-01

文章信息/Info

Title:
Efficacy Observation of Honghua Xiaoyao Tablet Combined with Tranexamic Acid Tablet and Hydroquinone Cream for liver-qi Stagnation Type Melasma
文章编号:
1001-7089(2019)05-0620-03
作者:
徐萍赵小兴
浙江绍兴第三医院皮肤科,浙江 绍兴 312000
Author(s):
XU PingZHAO Xiaoxing
(Department of Dermatology,Third Hospital of Shaoxing,Shaoxing 312000,China)
关键词:
红花逍遥片 氨甲环酸片 对苯二酚乳膏 黄褐斑
Keywords:
Honghua xiaoyao tabletTranexamic acid tabletHydroquinone creamMelasma
分类号:
R 758.4+2
DOI:
10.13735/j.cjdv.1001-7089.201803159
文献标志码:
B
摘要:
目的观察红花逍遥片联合氨甲环酸片、对苯二酚乳膏治疗肝郁气滞型黄褐斑临床疗效和安全性。方法选择102例女性肝郁气滞型黄褐斑患者随机分为两组,治疗组(52例)给予红花逍遥片联合氨甲环酸片、对苯二酚乳膏治疗,对照组(50例)给予氨甲环酸片联合对苯二酚乳膏治疗,两组患者均治疗12周。观察两组患者的临床疗效、治疗前后色斑的变化及不良反应发生的状况。结果治疗组与对照组有效率分别为80.77%和62.00%,差异有统计学意义(P<0.05)。两组患者治疗期间均未出现严重不良反应。结论红花逍遥片联合氨甲环酸片、对苯二酚乳膏治疗肝郁气滞型黄褐斑疗效显著,安全性高。
Abstract:
Objective To observe the efficacy and safety of Honghua xiaoyao tablet combined with Tranexamic acid tablet and Hydroquinone cream for melisma with liver qi stagnation.Methods One hundred and two female patients were randomly divided into 2 groups.Fifty two cases in the treatment group were given Honghua xiaoyao tablet, Tranexamic acid tablet and Hydroquinone cream for 12 weeks, while 50 cases treated with Tranexamic acid tablet and Hydroquinone cream served as controls.Clinical efficacy, changes in pigment and adverse reactions were assessed in both groups.ResultsThe effective rates in the treatment and the control groups were 80.77% and 62.00% respectively(P<0.05).Neither groups had severe adverse events.ConclusionHonghua xiaoyao tablet combined with Tranexamic acid tablet and Hydroquinone cream is effective and safe for melasma with liver qi stagnation.

参考文献/References:


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备注/Memo

备注/Memo:

[作者单位]浙江绍兴第三医院皮肤科,浙江 绍兴 312000
更新日期/Last Update: 2019-04-15