[1]宋翠豪,赵梓纲,李承新.SAPHO综合征5例并文献复习[J].中国皮肤性病学杂志,2018,(08):893-897.[doi: 10.13735/j.cjdv.1001-7089.201709116]
 SONG Cuihao,ZHAO Zigang,LI Chengxin.Five Cases of SAPHO Syndrome Report and Literature Review[J].The Chinese Journal of Dermatovenereology,2018,(08):893-897.[doi: 10.13735/j.cjdv.1001-7089.201709116]
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SAPHO综合征5例并文献复习
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2018年08期
页码:
893-897
栏目:
临床经验
出版日期:
2018-09-10

文章信息/Info

Title:
Five Cases of SAPHO Syndrome Report and Literature Review
作者:
宋翠豪赵梓纲李承新
解放军总医院皮肤科,北京 100853
Author(s):
SONG CuihaoZHAO ZigangLI Chengxin
Department of Dermatology,PLA General Hospital,Beijing 100853,China
关键词:
SAPHO综合征 诊断 治疗
Keywords:
Synovitis-Acne-Pustulosis-Hyperostosis-Osteitis syndrome Diagnosis Therapy
分类号:
R 758.6
DOI:
10.13735/j.cjdv.1001-7089.201709116
文献标志码:
B
摘要:
目的 探讨SAPHO 综合征的临床特征,提高临床医生对本病的认识。方法 回顾性分析5例SAPHO综合征患者相关资料,并结合文献讨论。结果 5例患者为4男1女,4例皮损表现为掌跖脓疱病,1例表现为聚合性痤疮。其骨关节损害均在皮肤损害之后出现。有4例患者行骨扫描检查,均有病变区的核素浓聚(可见牛头征)。5例均累及胸锁关节,1例累及腕关节、指关节、左侧踝关节。2例胸骨受累,1例足骨受累。结论 SAPHO 综合征具有一定的临床和影像学特点,可以为临床诊断提供帮助。
Abstract:
Objective To discuss the clinical features of SAPHO syndrome,and improve the understanding of the disease. Methods Five cases of SAPHO syndrome were reported and the related literature were reviewed. Results There were five patients including four males and one female in the study,four of which were manifested themselves as palmoplantar pustulosis and other one was acne conglobata. All skin lesions followed the onset of arthritis. Four patients were conducted the bone scanning,and the results showed that all of them had the concentration of nuclide in the lesion area(Bullhead sign). All five cases had sternoclavicular joints involvement,meanwhile wrist,knuckles and left ankle joints were affected only in one case. In addition,the sterna was affected in two cases,and foot bones were affected in one case. Conclusion Distinct clinical and imaging characteristics of SAPHO syndrome may be beneficial for the diagnosis.

参考文献/References:


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备注/Memo

备注/Memo:

[通讯作者] 李承新,E-mail: chengxinderm@163.com
更新日期/Last Update: 2018-08-01