[1]陈雪,闵仲生,吉津.帕米磷酸二钠治疗SAPHO综合征1例[J].中国皮肤性病学杂志,2018,(03):294-298.[doi:10.13735/j.cjdv.1001-7089.201706035]
 CHEN Xue,MIN Zhongsheng,JI Jin.A Case of SAPHO Syndrome Successfully Treated with Pamidronate Disodium[J].The Chinese Journal of Dermatovenereology,2018,(03):294-298.[doi:10.13735/j.cjdv.1001-7089.201706035]
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帕米磷酸二钠治疗SAPHO综合征1例
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2018年03期
页码:
294-298
栏目:
临床经验
出版日期:
2018-03-01

文章信息/Info

Title:
A Case of SAPHO Syndrome Successfully Treated with Pamidronate Disodium
作者:
陈雪闵仲生吉津
南京中医药大学附属医院皮肤科,江苏 南京 210029
Author(s):
CHEN XueMIN ZhongshengJI Jin
Department of Dermatology,Affiliated Hospital of Nanjing University of Chinese Traditional Medicine,Nanjing 210029,China
关键词:
SAPHO综合征 骨损害 帕米磷酸二钠
Keywords:
SAPHO syndrome Osteoarticular lesion Pamidronate disodium
分类号:
R 751; R 681
DOI:
10.13735/j.cjdv.1001-7089.201706035
文献标志码:
B
摘要:
患者女,60岁,双掌跖红斑脓疱、脱屑,反复发作5年,关节疼痛3年。全身骨显像示:全身骨多发异常,放射性浓聚影。使用白芍总苷、沙利度胺、甲氨蝶呤后疼痛未缓解,后使用帕米磷酸二钠,疼痛明显缓解,皮疹消退,随访4个月未再发。
Abstract:
A 60-year-old female presented with erythematous macules,pustulosis,desquamation on her palms and soles for 5 years and joint pain for 3 years.Bonescintigraphy imaging showed multiple bone abnormalities and nuclide accumulations.Total glucosides of whitepaeony,thalidomide and methotrexate could not relieve the pain.But the pain were relieved significantly and the rash disappeared following the treatment with pamidronate disodium.The follow-up for 4 months showed no recurrences.

参考文献/References:

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备注/Memo

备注/Memo:
[通讯作者] 闵仲生,E-mail:minzhsh@sina.com
更新日期/Last Update: 2018-03-01