[1]张曌,陈欣玥,周念,等.婴幼儿血管瘤皮肤镜下特征[J].中国皮肤性病学杂志,2018,(01):33-37.[doi:10.13735/j.cjdv.1001-7089.201706106]
　ZHANG Zhao,CHEN Xinyue,ZHOU Nian,et al.Dermoscopic Features of Infantile Hemangioma[J].The Chinese Journal of Dermatovenereology,2018,(01):33-37.[doi:10.13735/j.cjdv.1001-7089.201706106]
点击复制

婴幼儿血管瘤皮肤镜下特征
分享到：

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2018年01期
页码:
33-37
栏目:
临床经验
出版日期:
2018-01-01

文章信息/Info

Title:
Dermoscopic Features of Infantile Hemangioma
作者:
张曌; 陈欣玥; 周念; 舒虹
昆明医科大学附属昆明市儿童医院皮肤科,昆明 650034
Author(s):
ZHANG Zhao;  CHEN Xinyue;  ZHOU Nian;  SHU Hong
Department of Dermatology, Kunming Children's Hospital, Kunming Medical University, Kunming 650034, China
关键词:
婴幼儿血管瘤;  皮肤镜;  腔隙样结构;  血管结构;  皮肤镜浸润法
Keywords:
Infantile hemangioma;  Dermocsopy;  Lacunae;  Vascular structures;  Dermocsopy soakage
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201706106
文献标志码:
B
摘要:
目的 观察婴幼儿血管瘤在皮肤镜下的特征,以探讨皮肤镜用于无创性诊断婴幼儿血管瘤的可行性。方法 回顾性分析2016年7月-2017年1月本科确诊的67例婴幼儿血管瘤皮损的皮肤镜下特征和临床资料。结果 婴幼儿血管瘤皮肤镜下结构特征为:红色腔隙样结构、膨大扩张的血管结构、皮损周边血管结构、蓝紫色腔隙样结构、弥漫性红色结构。单因素回归分析显示,患者年龄和婴幼儿血管瘤皮肤镜下各结构特性无显著相关性。婴幼儿血管瘤依据皮肤镜下主要形态结构模式,可分为四型:以“鹅卵石”样红色腔隙样结构为主的血管瘤、以膨大扩张血管结构为主的血管瘤、以稀疏排列的红色腔隙样结构为主的血管瘤和以弥漫性红色结构为主的血管瘤。结论 婴幼儿血管瘤皮肤镜下具有特征性结构,皮肤镜可作为婴幼儿血管瘤无创性诊断手段。
Abstract:
Objective To investigate the dermoscopic feature of infantile hemangioma(IH), and to discuss the practical use of dermoscopy on noninvasive diagnosis in the field of infantile hemangioma.Methods The dermoscopic images and clinical data of IH lesions in 67 patients were retrospectively analyzed from July 2016 to January 2017 in the Department of Dermatology in Kunming Children's Hospital.Results The typical vascular patterns of IH lesions were red lacunae, dilated vessel, arounding vessel,bluish-purple lacunae,diffuse reddish.No significant association was found between age and vascular patterns by univariate analysis.Based on the dermoscopic appearances of vascular dominant features, IH can subdivide into four vascular forms, cobble-stone like red lacunae pattern, dilated vessel pattern, loosely arranged red lacunae pattern,diffuse reddish pattern.Conclusion There are characteristic features for IH at dermoscopy.Dermoscope is a effective, noninvasive diagnostic method to IH.

参考文献/References:

[1] Faustini K, Lam JM.Five things to know about.infantile hemangiomas[J].CMAJ, 2013, 185(7): 586.
[2] 中华医学会整形外科分会血管瘤和脉管畸形学组.血管瘤和脉管畸形诊断和治疗指南(2016版)[J].组织工程与重建外科杂志, 2016, 12(2):63-93,97.
[3] Dasgupta R, Fishman SJ.ISSVA classification[J].Semin Pediatr Surg, 2014, 23(4): 158-161.
[4] Haliasos EC, Kerner M, Jaimes N, et al.Dermoscopy for the pediatric dermatologist, part ii: dermoscopy of genetic syndromes with cutaneous manifestations and pediatric vascular lesions[J].Pediatr Dermatol, 2013, 30(2): 172-181.
[5] Toledo-Alberola F, Betlloch-Mas I,Cuesta-Montero L, et al.Abortive hemangiomas.description of clinical and pathological findings with special emphasis on dermoscopy[J].Eur J Dermatol, 2010, 20(4): 497-500.
[6] Oiso N, Kimura M, Kawara S, et al.Clinical, dermoscopic, and histopathologic features in a case of infantile hemangioma without proliferation[J].Pediatr Dermatol, 2011, 28(1): 66-68.
[7] RAG R.Estructuras dermatoscópicas en hemangiomas infantiles[J].Dermatol Rev Mex, 2012, 56(3): 157-161.
[8] Oiso N, Kawada A.The dermoscopic features in infantile hemangioma[J].Pediatr Dermatol, 2011, 28(5): 591-593.
[9] Miyake M, Oiso N, Kawada A.Dermoscopic appearances in the superficial and deep type of infantile hemangioma[J].Cosmet Dermatol Sci Appl, 2012, 2(3): 212-213.
[10] Darrow DH, Greene AK, Mancini AJ, et al.Diagnosis and management of infantile hemangioma: executive summary[J].Pediatrics, 2015, 136(4): 786-791.
[11] Thomas L, Phan A, Pralong P, et al.Special locations dermoscopy: facial, acral, and nail[J].Dermatol Clin, 2013, 31(4): 615-624.
[12] Hofmann-Wellenhof R.Special criteria for special locations 2: scalp, mucosal, and milk line[J].Dermatol Clin, 2013, 31(4):625-636.
[13] Shirakawa M, Ozawa T, Wakami S, et al.Utility of Dermoscopy before and after Laser Irradiation in Port Wine Stains[J].Ann Dermatol, 2012, 24(1): 7-10.

相似文献/References:

[1]罗亚楠,黄远红,冯雷,等.VEGF和DLL4在婴幼儿血管瘤组织中的表达及相关性[J].中国皮肤性病学杂志,2016,(03):225.[doi:10.13735/j.cjdv.1001-7089.201507039]
　LUO Ya nan,HUANG Yuan hong,FENG Lei,et al.Expression of VEGF and DLL4 in Infantile Hemangioma Tissue and Correlation of Them[J].The Chinese Journal of Dermatovenereology,2016,(01):225.[doi:10.13735/j.cjdv.1001-7089.201507039]
[2]李倩男,孔祥君,韦伟,等.遗传性对称性色素异常症家系调查[J].中国皮肤性病学杂志,2016,(07):719.[doi:10.13735/j.cjdv.1001-7089.201510159]
　LI Qian-nan,KONG Xiang-jun,WEI wei,et al.Dyschromatosis Symmetrica Hereditaria and Their Families[J].The Chinese Journal of Dermatovenereology,2016,(01):719.[doi:10.13735/j.cjdv.1001-7089.201510159]
[3]韩晓锋,张立新,周春菊,等.儿童Hutchinson氏征阳性纵行黑甲32例临床分析[J].中国皮肤性病学杂志,2016,(08):799.[doi:10.13735/j.cjdv.1001-7089.201603071]
　HAN Xiao-feng,ZHANG Li-xin,ZHOU Chun-ju,et al.Clinical, Dermoscopic and Histopathologic Analysis of 32 Cases of Longitudinal Melanonychia with Hutchinson Sign in Children[J].The Chinese Journal of Dermatovenereology,2016,(01):799.[doi:10.13735/j.cjdv.1001-7089.201603071]
[4]章若画,闵仲生,谭城,等.运用22MHz高频超声对银屑病指甲的观测分析[J].中国皮肤性病学杂志,2017,(04):375.[doi:10.13735/j.cjdv.1001-7089.201609116]
　ZHANG Ruo-hua,MIN Zhong-sheng,TAN Cheng,et al.Observation and Analysis in Psoriasis Nails by 22MHz High-frequency Ultrasonography[J].The Chinese Journal of Dermatovenereology,2017,(01):375.[doi:10.13735/j.cjdv.1001-7089.201609116]
[5]党延玲,刘亚乐,曾维惠,等.皮肤镜在铒玻璃点阵激光治疗痤疮疗效观察中的应用[J].中国皮肤性病学杂志,2017,(05):508.[doi:10.13735/j.cjdv.1001-7089.201607153]
　DANG Yan-ling,LIU Ya-le,ZENG Wei-hui,et al.Application of Dermoscopy in Assessing the Efficacy of Erbium Laser for Acne Vulgaris[J].The Chinese Journal of Dermatovenereology,2017,(01):508.[doi:10.13735/j.cjdv.1001-7089.201607153]
[6]王静,赵卓,王艳红,等.辽宁省婴幼儿血管瘤及其相关因素的Logistic回归分析[J].中国皮肤性病学杂志,2017,(06):619.[doi:10.13735/j.cjdv.1001-7089.201609068]
　WANG Jing,ZHAO Zhuo,WANG Yan-hong,et al.Unconditional Logistic Regression Analysis of Risk Factors for Infantile Hemangioma in Liaoning Province[J].The Chinese Journal of Dermatovenereology,2017,(01):619.[doi:10.13735/j.cjdv.1001-7089.201609068]
[7]王瑞,董正邦,王飞.获得性反应性穿通性胶原病1例[J].中国皮肤性病学杂志,2017,(08):892.[doi:10.13735/j.cjdv.1001-7089.201702094]
　WANG Rui,DONG Zheng-bang,WANG Fei.A Case of Acquired Reactive Perforating Collagenosis[J].The Chinese Journal of Dermatovenereology,2017,(01):892.[doi:10.13735/j.cjdv.1001-7089.201702094]
[8]方杰,张艾丽,袁伟,等.不典型Becker痣1例的皮肤镜表现[J].中国皮肤性病学杂志,2017,(10):1129.[doi:10.13735/j.cjdv.1001-7089.201704083]
　FANG Jie,ZHANG Ai-li,YUAN Wei,et al.The Dermatoscopic Features of a Case of Atypical Becker's Nevus[J].The Chinese Journal of Dermatovenereology,2017,(01):1129.[doi:10.13735/j.cjdv.1001-7089.201704083]
[9]徐小茜,游紫梦,代亚玲,等.儿童面部毳毛癣皮肤镜、荧光染色及扫描电镜观察1例[J].中国皮肤性病学杂志,2018,(03):299.[doi:10.13735/j.cjdv.1001-7089.201708063]
　XU Xiaoxi,YOU Zimeng,DAI Yaling,et al.Dermoscopic,Fluorescence Staining and Scanning Electronic Microscopic Observation on Facial Tinea of Vellus Hair in a Child[J].The Chinese Journal of Dermatovenereology,2018,(01):299.[doi:10.13735/j.cjdv.1001-7089.201708063]
[10]贺月华,冯雷,罗亚楠,等.EGFL7和FAK在婴幼儿血管瘤组织中的表达及其相关性[J].中国皮肤性病学杂志,2018,(06):620.[doi:10.13735/j.cjdv.1001-7089.201711097]
　HE Yuehua,FENG Lei,LUO Ya'nan,et al.Expression and Correlation of EGFL7 and FAK in Infantile Hemangioma[J].The Chinese Journal of Dermatovenereology,2018,(01):620.[doi:10.13735/j.cjdv.1001-7089.201711097]
[11]冉玉平,徐小茜,冉昕,等.伊曲康唑口服液治愈婴儿血管瘤1例:皮肤镜监测血管瘤消退情况[J].中国皮肤性病学杂志,2017,(01):45.[doi:10.13735/j.cjdv.1001-7089.201607074]
　RAN Yu-ping,XU Xiao-xi,RAN Xin,et al.A Case of Infantile Hemangioma Successfully Treated by Itraconazole Oral Solution: Dermoscopy Monitory the Vascular Regression[J].The Chinese Journal of Dermatovenereology,2017,(01):45.[doi:10.13735/j.cjdv.1001-7089.201607074]

备注/Memo

备注/Memo:
[基金项目] 昆明市卫计委“十百千”儿童血管瘤诊疗技术中心(SW(技)-65)
[通讯作者] 舒虹,E-mail:kmsh333@163.com
更新日期/Last Update: 2018-01-05