[1]王珊,马琳.湿包裹治疗在儿童重度特应性皮炎中的应用[J].中国皮肤性病学杂志,2017,(12):1377-1379.[doi:10.13735/j.cjdv.1001-7089.201703077]
 WANG Shan,MA Lin.The Use of Wet-wrap in Treatment of Severe Atopic Dermatitis in Children[J].The Chinese Journal of Dermatovenereology,2017,(12):1377-1379.[doi:10.13735/j.cjdv.1001-7089.201703077]
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湿包裹治疗在儿童重度特应性皮炎中的应用
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2017年12期
页码:
1377-1379
栏目:
综述
出版日期:
2017-11-20

文章信息/Info

Title:
The Use of Wet-wrap in Treatment of Severe Atopic Dermatitis in Children
作者:
王珊 马琳
国家儿童医学中心首都医科大学附属北京儿童医院皮肤科,北京 100045
Author(s):
WANG ShanMA Lin
Department of Dermatology,Beijing Children's Hospital,Capital Medical University National Center for Children's Health,Beijing 100045,China
关键词:
湿包裹 特应性皮炎 治疗 儿童 管状绷带
Keywords:
Wet-wrap Atopic dermatitis Treatment Children Tubular bandages
分类号:
R 758.2
DOI:
10.13735/j.cjdv.1001-7089.201703077
文献标志码:
A
摘要:
儿童重度特应性皮炎(atopic dermatitis,AD)因系统用药受年龄及不良反应的限制常缺乏有效治疗方法,而湿包裹治疗(wet-wrap treatment,WWT)是对反复难治性重度AD的一种有效且相对安全的方法。WWT是指在外用药物及润肤的基础上,使用双层管状绷带或纱布包裹治疗的一种治疗模式。在国际上广泛用于治疗各种瘙痒性皮肤疾病,尤其是儿童重度AD,与传统外用药物治疗比较的优势在于起效迅速、修复皮肤屏障,并显著控制瘙痒,从而改善生活质量,同时减少系统药物的应用。WWT目前报告不良反应较少,通常较轻微,且为一过性。该方法在国内尚无相关报道。
Abstract:
Treatment of severe atopic dermatitis(AD)in children is especially challenging because of the limitation of systemic treatment in consideration of age and adverse effects. Wet-wrap treatment(WWT)is a relatively safe and effective intervention for severe or refractory AD in children. WWT is a modality using double layers of bandages,cotton clothing,or gauze in addition to topical medication and emollient. WWT is widely used to treat various pruritic dermatosis,in particular,severe AD in children. Compared with traditional topical treatments,the advantages of WWT include quicker effect,repair of skin barrier function,and alleviation of pruritus,leading to improvement of the life quality and reduction in the use of systemic agents. The adverse reactions of WWT are fewer,and usually mild and transient. This method has not been reported in our country.

参考文献/References:

[1] Weidinger S,Novak N.Atopic dermatitis[J].Lancet,2016,387(10023):1109-1122.
[2] Nicol NH,Boguniewicz M. Wet wrap therapy in moderate to severe atopic dermatitis[J]. Immunol Allergy Clin North Am,2017,37(1):123-139.
[3] Bingham LG,Noble JW,Davis MD. Wet dressings used with topical corticosteroids for pruritic dermatoses:a retrospective study[J]. J Am Acad Dermatol,2009,60(5):792-800.
[4] Quinones CA,Winkelmann RK. Changes in skin temperature with wet dressing therapy[J]. Arch Dermatol,1967,96(6):708-711.
[5] Oranje AP,Devillers AC,Kunz B,et al. Treatment of patients with atopic dermatitis using wet-wrap dressings with diluted steroids and/or emollients. An expert panel's opinion and review of the literature[J]. J Eur Acad Dermatol Venereol,2006,20(10):1277-1286.
[6] Devillers AC,Oranje AP. Wet-wrap treatment in children with atopic dermatitis:a practical guideline[J]. Pediatr Dermatol,2012,29(1):24-27.
[7] Eichenfield LF,Tom WL,Berger TG,et al. Guidelines of care for the management of atopic dermatitis:Section 2. Management and treatment of atopic dermatitis with topical therapies[J]. J Am Acad Dermatol,2014,71(1):116-132.
[8] Barham KL,Yosipovitch G. It's a wrap:the use of wet pajamas in wet-wrap dressings for atopic dermatitis[J]. Dermatol Nurs,2005,17(5):365-367.
[9] Nicol NH,Boguniewicz M,Strand M,et al. Wet wrap therapy in children with moderate to severe atopic dermatitis in a multidisciplinary treatment program[J]. J Allergy Clin Immunol,2014,2(4):400-406.
[10] Lee JH,Lee SJ,Kim D,et al. The effect of wet-wrap dressing on epidermal barrier in patients with atopic dermatitis[J]. J Eur Acad Dermatol Venereol,2007,21(10):1360-1368.
[11] Dabade TS,Davis DMR,Wetter DA,et al. Wet dressing therapy in con-junction with topical corticosteroids is effective for rapid control of severe pediatric atopic dermatitis:experience with 218 patients over 30 years at Mayo Clinic[J]. J Am Acad Dermatol,2012,67(1):100-106.
[12] Hwang SM,Ahn SK,Menon GK,et al. Basis of occlusive therapy in psoriasis:correcting defects in permeability barrier and calcium gradient[J]. Int J Dermatol,2001,40(3):223.
[13] Nicol NH,Boguniewicz M. Successful strategies in atopic dermatitis management[J]. Dermatol Nurs,2008(Suppl):3.
[14] Janmohamed SR,Oranje AP,Devillers AC,et al. The proactive wet-wrap method with diluted corticosteroids versus emollients in children with atopic dermatitis:a prospective,randomized,double-blind,placebo-controlled trial[J]. J Am Acad Dermatol,2014,70(6):1076-1082.
[15] Albarrán-Planelles C,Jiménez-Gallo D,Linares-Barrios M,et al. Our experience with wet-wrap treatment[J]. Actas Dermosifiliogr,2014,105(3):e18-21.
[16] Devillers AC,Oranje AP. Efficacy and safety of wet-wrap dressings as an intervention treatment in children with severe and/or refractory atopic dermatitis:a critical review of the literature[J]. Br J Dermatol,2006,154(4):579-585.
[17] Andersen RM,Thyssen JP,Maibach HI. The role of wet wrap therapy in skin disorders - a literature review[J]. Acta Dermato-Venereologica,2015,95(8):933.
[18] Devillers AC,de Waard-van der Spek FB,Mulder PG,et al. Treatment of refractory atopic dermatitis using “wet-wrap” dressings and diluted corticosteroids:results of standardized treatment in both children and adults[J]. Dermatol,2002,204(1):50-55.

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更新日期/Last Update: 2017-12-01