[1]卢井发,黄雪娇,曾招林,等.雅漾三重修护特润霜联合丁酸氢化可的松乳膏治疗婴幼儿湿疹/特应性皮炎临床观察[J].中国皮肤性病学杂志,2017,(05):585-587.[doi:10.13735/j.cjdv.1001-7089.201609033]
 LU Jing-fa,HUANG Xue-jiao,ZENG Zhaolin,et al.Efficacy of Avene Trixeta Emollient Cream Combined with Hydrocortisone Butyrate Cream for Infantile Eczema and Atopic Dermatitis[J].The Chinese Journal of Dermatovenereology,2017,(05):585-587.[doi:10.13735/j.cjdv.1001-7089.201609033]
点击复制

雅漾三重修护特润霜联合丁酸氢化可的松乳膏治疗婴幼儿湿疹/特应性皮炎临床观察
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2017年05期
页码:
585-587
栏目:
药物与临床
出版日期:
2017-05-01

文章信息/Info

Title:
Efficacy of Avene Trixeta Emollient Cream Combined with Hydrocortisone Butyrate Cream for Infantile Eczema and Atopic Dermatitis
作者:
卢井发1黄雪娇2曾招林1万春雷1叶小英1
1.赣南医学院第一附属医院皮肤科,江西 赣州 341000; 2.赣南医学院第一附属医院心脏介入室,江西 赣州 341000
Author(s):
LU Jing-fa1 HUANG Xue-jiao2ZENG Zhaolin1 WAN Chun-lei1 YE Xiao-ying1
1.Department of dermatology,the First Affiliated Hospital of Gannan Medical College, Ganzhou 341000,China; 2.Catdiac interventional cardiology,the First Affiliated Hospital of Gannan Medical College,Ganzhou 341000,China
关键词:
雅漾三重修护特润霜 丁酸氢化可的松乳膏 湿疹 特应性皮炎 婴幼儿
Keywords:
Avene trixeta emollient cream Hydrocortisone butyrate cream Eczema Atopic dermatitis Infant
分类号:
R 758.23
DOI:
10.13735/j.cjdv.1001-7089.201609033
文献标志码:
B
摘要:
目的 评价雅漾三重修护特润霜联合丁酸氢化可的松乳膏治疗婴幼儿湿疹和特应性皮炎的临床疗效和安全性。方法 将入选的121例患者按就诊顺序编号后,采用随机数字表法入选将患者分为三组,治疗组(37例)予雅漾三重修护特润霜联合丁酸氢化可的松乳膏外搽,对照1组(41例)予雅漾三重修护特润霜外搽,对照2组(43例)予丁酸氢化可的松乳膏外搽,均2次/d,疗程2周,分别于治疗1周、2周后观察其疗效及不良反应。结果 治疗2周后治疗组、对照1组和对照2组有效率依次为94.6%、63.41%和79.07%,治疗组有效率高于其他两组患儿的有效率,且差异均有统计学意义(P均<0.05)。三组患儿均未出现明显不良反应。结论 雅漾三重修护特润霜对治疗婴幼儿湿疹和异位性皮炎有良好的辅助治疗作用,联合应用丁酸氢化可的松软膏后可明显提高临床疗效,值的临床医生选用。
Abstract:
Objective To study the clinical efficacy and safety of avene trixeta emollient cream combined with hydrocortisone butyrate cream in the treatment of infantile eczema and atopic dermatitis.Methods A total of 121 patients were divided into three groups according the order of clinical visit.The treatment group(37)was treated with avene trixeta emollient cream combined with hydrocortisone butyrate cream; Control group 1(41)and 2(43)were treated with avene trixeta emollient cream and hydrocortisone butyrate cream, respectively.All of the patients were treated twice daily for 2 weeks.Efficacy and adverse reactions were evaluated 1 week and 2 weeks after the treatment.Results After 2-weeks the effective rates in treatment group were higher than that in control group 1 and 2(94.6% vs.63.41% and 79.07%, p<0.05 treatment vs.both controls).No notable adverse reactions were found in any group.Conclusion Avene trixeta emollient cream is an effective adjuvant for the treatment of infantile eczema and atopic dermatitis.Combination of avene trixeta emollient cream with hydrocortisone butyrate improves efficacy.It is worth to use it.

参考文献/References:

[1] 中华医学会皮肤性病学分会免疫学组.湿疹诊疗指南(2011年)[J].中华皮肤科杂志,2011,44(1):5-6.
[2] 中华医学会皮肤性病学分会免疫学组、特应性皮炎协作研究中心.中国特应生皮炎诊疗指南(2014版)[J].中华皮肤科杂志,2014,47(7):511-514.
[3] 赵辨.湿疹面积及严重度指数评分法[J].中华皮肤科杂志,2004,37(1):3-4.
[4] 李琳,张悦,程岩峰,等.尤卓尔联合三重修护特润霜治疗婴幼儿湿疹的疗效[J].实用药物与临床,2013,16(5):419-421.
[5] 吴琰瑜,王学民.外用糖皮质激素对皮肤屏障系统的影响[J].国际皮肤性病学杂志,2011,37(5)289-291.
[6] 施佳音,张秀红,杨挺,等.丝塔芙润肤露在婴幼儿湿疹治疗中的辅助作用观察[J].中国皮肤性病学杂志,2011,25(11):916-918.
[7] Hon KL, Pong NH, Wang SS, et al.Acceptability and Efficacy of an Emollient Containing Ceramide- Precursor Lipids and Moisturizing Factors for Atopic Dermatitis in Pediatric Patients[J].Drugs R D, 2013,13(1):37-42.
[8] ?倗 kerstr ?倠 m U, Reitamo S, Langeland T, et al.Comparison of Moisturizing Creams for the Prevention of Atopic Dermatitis Relapse: A Randomized Double-blind Controlled Multicentre Clinical Trial[J].Acta Derm Venereol, 2015, 95(5): 587-592
[9] 唐萍,谭琦,王华.皮肤屏障关键结构与特应性皮炎的相关性[J].激光杂志, 2013,34(5)118-122.
[10] 何黎.重建皮肤屏障在湿疹治疗中的重要性[J].皮肤病与性病,2009,31(3):12-13.
[11] 吴艳,杜丽霞,陈璨,等.含马齿苋及牛油果树提取物护肤品对乏脂性湿疹临床效果观察[J].临床皮肤科杂志,2009,38(6):349-351.
[12] 李谦,孙东杰,何黎,等.薇诺娜柔润保湿霜对慢性湿疹辅助治疗作用的观察[J].中国皮肤性病学杂志,2012, 26(7):601-604.

相似文献/References:

[1]陈君,刘珏,吴黎明.透明质酸凝胶联合丁酸氢化可的松乳膏治疗婴幼儿湿疹100例临床观察[J].中国皮肤性病学杂志,2017,(01):112.[doi:10.13735/j.cjdv.1001-7089.201601139]
 CHEN Jun,LIU Jue,WU Li-ming.Clinical Observationof Hyaluronic Acid Gel Combined with Hydrocortisone Butyrate Cream for Treating of 100 Patients with Infantile Eczema[J].The Chinese Journal of Dermatovenereology,2017,(05):112.[doi:10.13735/j.cjdv.1001-7089.201601139]
[2]毛治芳.心理干预对神经性皮炎疗效的影响[J].中国皮肤性病学杂志,2013,(02):156.

备注/Memo

备注/Memo:
[基金项目] 赣州市指导性科技计划项目(GZ2015ZSF077)
更新日期/Last Update: 2017-05-10