[1]欧阳飞.凉血解毒消风药治疗血热型银屑病的临床疗效与安全性[J].中国皮肤性病学杂志,2016,(09):949-951.[doi:10.13735/j.cjdv.1001-7089.201603133]
 Ou Yang-fei.The Efficacy and Safety of Blood-cooling and Wind-dispelling Medicine in Treating Blood Heat Type of Psoriasis[J].The Chinese Journal of Dermatovenereology,2016,(09):949-951.[doi:10.13735/j.cjdv.1001-7089.201603133]
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凉血解毒消风药治疗血热型银屑病的临床疗效与安全性
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2016年09期
页码:
949-951
栏目:
中医中药
出版日期:
2016-09-01

文章信息/Info

Title:
The Efficacy and Safety of Blood-cooling and Wind-dispelling Medicine in Treating Blood Heat Type of Psoriasis
作者:
欧阳飞
遂宁市中心医院,四川 遂宁 629000
Author(s):
Ou Yang-fei
Central Hospital of Suining,Suining 629000,China
关键词:
凉血解毒消风 血热型 银屑病 疗效 安全性
Keywords:
Blood-cooling and wind-dispeling Blood heat type Psoriasis Efficacy Safety
分类号:
R 758.63
DOI:
10.13735/j.cjdv.1001-7089.201603133
文献标志码:
B
摘要:
目的 探讨凉血解毒消风药治疗血热型银屑病的临床疗效与安全性。方法 选取2013年8月-2015年12月在我院皮肤科就诊的血热型银屑病患者120例,随机均分为治疗组与对照组,治疗组采用凉血解毒消风药煎汤内服,对照组给予复方青黛胶囊口服; 比较两组患者治疗前后PASI总分、临床疗效及不良反应发生情况。结果 两组患者治疗后PASI总分均显著低于治疗前(P<0.05),且治疗组显著低于对照组(P<0.05)。治疗组总有效率78.33%(47/60),显著高于对照组的60.00%(36/60)(P<0.05)。治疗后患者不良反应发生率分别为:治疗组10.00%(6/60)、对照组5.00%(3/60),其中稀便为主要不良反应,两组比较差异无统计学意义(P>0.05)。两组患者治疗前后血常规、肝肾功指标比较差异均无统计学意义(p>0.05)。结论 采用凉血解毒消风药治疗血热型银屑病疗效确切,且具有较好的安全性,临床疗效优于复方青黛胶囊。
Abstract:
Objective To explore the clinical efficacy and safety of blood-cooling wind-dispelling medicines in treating blood heat type of psoriasis. Methods One hundred and twenty patients with blood heat type of psoriasis were enrolled at our hospital from August 2013 to December 2015, and randomly divided into the treatment and the control group. Treatment group were given decoction of blood-cooling wind-dispelling medicines while the control group were given compound Qingdai capsules. PASI score, clinical efficacy and adverse reactions were compared in both groups before and after treatment. Results Both treatments significantly lowered PASI scores(P < 0.05). And PASI scores were lower in the treatment group than in the controls(P < 0.05). Total effective rate was significantly higher in the treatment group than in the controls [78.33%(47/60)vs 60.00%(36/60), P < 0.05]. The incidence of adverse reactions in the treatment and the control group were 10.00%(6/60)and 5.00%(3/60), respectively. Loose stool was the major adverse reaction. There was no difference in the incidence of loose stool between the two groups(P >0.05). The blood routine test, and tests of liver and kidney function were no differences between the two groups either before or after treatment(P> 0.05).Conclusion Blood-cooling and wind-dispelling medicines are effective and safe for blood heat type of psoriasis, and superior to compound Qindai capsules.

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更新日期/Last Update: 2016-09-20