[1]李浩,李铁男,刘晓明,等.老年过敏性紫癜42例临床分析[J].中国皮肤性病学杂志,2016,(05):475-476，526.[doi:10.13735/j.cjdv.1001-7089.201506094]
　LI Hao,LI Tie nan,LIU Xiao ming,et al.Clinical Analysis of 42 Elderly Cases with HenochSchnlein Purpura[J].The Chinese Journal of Dermatovenereology,2016,(05):475-476，526.[doi:10.13735/j.cjdv.1001-7089.201506094]
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老年过敏性紫癜42例临床分析
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2016年05期
页码:
475-476，526
栏目:
临床经验
出版日期:
2016-05-01

文章信息/Info

Title:
Clinical Analysis of 42 Elderly Cases with HenochSchnlein Purpura
作者:
李浩1; 李铁男1; 刘晓明2; 刘岩1; 李上云1
1沈阳市第七人民医院皮肤科，辽宁 沈阳 110003；2香港大学深圳医院皮肤科，广东 深圳 518053
Author(s):
LI Hao1; LI Tienan1; LIU Xiaoming2; LIU Yan1; LI Shangyun1
1Department of Dermatology, the Seventh Hospital of Shenyang, Shenyang 110003, China；2The University of Hong KongShenzhen Hospital, Shenzhen 518053,China
关键词:
过敏性紫癜; 老年
Keywords:
HenochSchnlein purpura; Elderly
分类号:
R 554+6
DOI:
10.13735/j.cjdv.1001-7089.201506094
文献标志码:
B
摘要:
目的 探讨老年过敏性紫癜患者的临床表现、实验室检查、治疗及预后。 方法 回顾性分析本院收治的42例60~81岁老年过敏性紫癜患者的临床资料。 结果 42例老年过敏性紫癜患者中，发病高峰为4~7月。皮疹泛发周身23例(5476%)，关节受累7例(1667%)，消化道受累8例(1905%)，肾脏受累28例(6667%)，6~12个月后尿常规检查结果恢复正常为11例(3929%)。合并感染9例(2143%)，贫血28例(6667%)，低蛋白血症17例(4048%)。每天予泼尼松20~130mg治疗14例(3333%)，应用雷公藤多甙片20~60mg治疗3例(714%)，应用沙利度胺片50~100mg治疗2例(476%)。住院10~46d，平均1735d。 结论 老年过敏性紫癜患者皮疹易泛发周身，肾脏比关节和消化道更易受累，且不易恢复。患者易合并低蛋白血症，且病程较长，必要时需加用激素及免疫抑制剂等控制病情。
Abstract:
Objective To investigate the clinical manifestations, laboratory examination, therapy and prognosis of the elderly cases with HenochSchnlein purpura Methods To retrospectively analyze the clinical data of 42 cases of 60~81 years old elderly hospitalized patients diagnosed as HenochSchnlein purpura Results Fortytwo elderly patients diagnosed as HenochSchnlein purpura, the peak months being April to JulyThe erythema of 23 cases(5476%) developed all over the bodySeven cases (1667%) involved in the arthralgiaEight cases (1905%) involved in digestive tract symptomTwentyeight cases (6667%) involved in purpura kidneyThe routine urine test of 11 cases(3929%)restored to normal after 6~12 monthsThe elderly patients, 9 cases(2143%) involved in infection，28 cases(6667%) involved in anaemia,17 cases(4048%) involved in hypoproteinemiaThe 42 patients, 14 cases(3333%) were treated with prednisone 20~130mg/d, 3 cases(714%) were treated with Lei Gongteng 20~60mg/d, 2 cases(476%) were treated with thalidomide 50~100mg/dThe hospitalization time was 10~46 days, and the mean was 1735 daysConclusion The elderly HenochSchnlein purpura patients, developed erythema all over the body easily, kidney more susceptible involved than joint and digestive tract, and rehabilitation was difficultThe patients were more frequently complicated with hypoproteinemiaThe course of disease was long, and some patients were treated with glucocorticoid，immunosuppressant to control the disease, when necessary

参考文献/References:

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更新日期/Last Update: 2016-05-20