[1]郑结成,徐宁,张杰,等.疑似面部化妆品变应性接触性皮炎58例斑贴试验[J].中国皮肤性病学杂志,2016,(04):369-371,379.[doi:10.13735/j.cjdv.1001-7089.201510139]
 ZHENG Jie cheng,XU Ning,ZHANG Jie,et al.The Patch Test Results of 58 Cases of Suspected Facial Cosmetic Allergic Contact Dermatitis[J].The Chinese Journal of Dermatovenereology,2016,(04):369-371,379.[doi:10.13735/j.cjdv.1001-7089.201510139]
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疑似面部化妆品变应性接触性皮炎58例斑贴试验
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2016年04期
页码:
369-371,379
栏目:
论著
出版日期:
2016-04-01

文章信息/Info

Title:
The Patch Test Results of 58 Cases of Suspected Facial Cosmetic Allergic Contact Dermatitis
作者:
郑结成12徐宁2张杰2周静2窦侠2于波12
1.安徽医科大学北京大学深圳医院临床学院,广东 深圳 518000;2.北京大学深圳医院,广东 深圳 518000
Author(s):
ZHENG Jiecheng12 XU Ning2ZHANG Jie2 ZHOU Jing2 DOU Xia2 YU Bo12
1.Clinical institute of Peking University Shenzhen hospital, Anhui Medical University, Shenzhen 518000, China;2.Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen 518000, China
关键词:
化妆品接触性皮炎斑贴试验过敏原
Keywords:
Cosmetic Contact dermatitis Patch test Allergen
分类号:
R 758.2
DOI:
10.13735/j.cjdv.1001-7089.201510139
文献标志码:
B
摘要:
目的 调查化妆品相关变应原,为疑诊化妆品变应性接触性皮炎的患者进行临床治疗指导及预防。方法 对来自本科门诊的58例疑诊化妆品接触性皮炎患者进行化妆品系列变应原斑贴试验,部分患者同时进行欧洲标准系列变应原斑贴试验,按国际接触性皮炎研究组推荐标准判读结果。结果 58例患者中,化妆品系列斑贴试验阳性率5862%,最常见的化妆品变应原为卡松CG(3103%)及甲基异噻唑啉酮(2931%),在所有的阳性反应中,防腐剂类变应原所占比例最高,为7759%;欧洲标准系列的化妆品相关变应原中阳性率最高的为卡松CG(2162%),标准系列中化妆品相关变应原与化妆品系列变应原阳性结果呈中等一致性。结论 防腐剂类是化妆品变应性接触性皮炎患者最主要的过敏原。
Abstract:
Objective To investigate cosmetic products related allergens and provide clinical guidance for suspected facial cosmetic allergic contact dermatitis patients. Methods Patch test of cosmetic series allergens was performed on 58 patients with suspected cosmetic allergic contact dermatitis. Thirty-seven patients were also tested by European standard series allergens at the same time. The positive reactions were determined according to the international contact dermatitis research group recommendation. Results Of the 58 patients patch test with cosmetic series, 34 (58.62%) patients showed at least one positive reaction. The most common allergen was Kathon CG (31.03%),which belonged to preservative allergens. Of the 37 patients patch test by European standard series allergens, 24 (64.86%) showed positive reactions. Conclusion Preservatives including Kathon CG, Methylisothiazolinone are the most common allergens inducing the cosmetic allergic contact dermatitis.

参考文献/References:

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备注/Memo

备注/Memo:
[基金项目] 深圳市知识创新计划基础研究项目(JCYJ20140415162542993)
更新日期/Last Update: 2016-04-20