[1]张玉红,高明敏,肖春才,等.润燥止痒胶囊联合依匹斯汀胶囊治疗老年瘙痒症49例临床观察[J].中国皮肤性病学杂志,2016,(02):216-218.[doi:10.13735/j.cjdv.1001-7089.201503102]
　ZHANG Yu hong,GAO Ming min,XIAO Chun cai,et al.The Clinical Observation of Runzaozhiyang Capsule Combined with Epinastine Capsule for Treating 49 Cases of Senile Pruritus[J].The Chinese Journal of Dermatovenereology,2016,(02):216-218.[doi:10.13735/j.cjdv.1001-7089.201503102]
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润燥止痒胶囊联合依匹斯汀胶囊治疗老年瘙痒症49例临床观察
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2016年02期
页码:
216-218
栏目:
药物与临床
出版日期:
2016-02-01

文章信息/Info

Title:
The Clinical Observation of Runzaozhiyang Capsule Combined with Epinastine Capsule for Treating 49 Cases of Senile Pruritus
作者:
张玉红; 高明敏; 肖春才; 王冬鸽
郑州大学附属郑州中心医院皮肤科,河南 郑州 450007
Author(s):
ZHANG Yuhong; GAO Mingmin; XIAO Chuncai; WANG Dongge
Department of Dermatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007，China
关键词:
瘙痒症; 老年; 润燥止痒胶囊; 依匹斯汀胶囊; 临床观察
Keywords:
Pruritus; senile; Runzaozhiyang capsule; Epinastine capsule; Clinical observation
分类号:
R 7583
DOI:
10.13735/j.cjdv.1001-7089.201503102
文献标志码:
B
摘要:
目的 评价润燥止痒胶囊联合依匹斯汀胶囊治疗老年瘙痒症的临床疗效和安全性。 方法 将入选的98例老年瘙痒症患者随机分成两组，各49例，均予甘油薄荷擦剂适量外擦患处，润燥止痒胶囊20g口服，均3次/d。治疗组同时每晚还予依匹斯汀胶囊10mg口服，治疗4周后判定疗效。 结果 治疗组有效率为7551%，对照组为4898%，皮肤病生活质量指数和临床症状评分结果显示，治疗组比对照组显著降低，且以上差异均有统计学意义(P均<005)。两组未出现明显不良反应。 结论 润燥止痒胶囊联合依匹斯汀胶囊治疗老年瘙痒症效果显著。
Abstract:
Objective To observe the clinical efficacy and safety of Runzaozhiyang capsule combined with epinastine capsule in treatment of senile pruritus Methods Ninetyeight cases of senile pruritus were randomly divided into treatment group and control group.Two groups were treated with external application of glycerol mint liniment and 20g Runzaozhiyang capsules three times a day.The 49 cases of treatment group with the same scheme plus 10mg epinastine capsule once orally every night.Four weeks of medication for both groups Results The effective rate in treatment group was 7551%，the control group was 4898%.DLQI and clinical symptom score in treatment group was significantly reducedThere was significant difference between the two groups(P<005)No serious adverse reactions were found Conclusion Runzaozhiyang capsule combined with epinastine capsule can treat senile pruritus effectively and safely

参考文献/References:

[1] 赵辨.临床皮肤病学[M].3版.南京：江苏科学技术出版社，2001:707-709.
[2] 沈伟国，〖JP+1〗赵设计.中西医结合治疗老年性〖LL〗皮肤瘙痒症疗效观察[J].实用临床学，2005，6(6):96-97.
[3] Finlay AY，Khan GK.Dermatology life quality index(DLQI)a simple practical measure for routine clinical use[J].Clin Exp Dermatol，1994，19(3):210-216.
[4] 郭宏昌，王淑玲.白细胞介素2与中医药关系研究概况[J].河南中医，2001，21(5):75，78-79.
[5] 王文静，薛咏梅，赵荣华，等.何首乌的化学成分和药理作用研究进展[J].云南中医学院学报，2007，30(3):60-64.
[6] 〖JP2〗樊宏伟，卢继红，张蓉.苦参碱类生物碱的体外抑菌、抑制病毒及诱生干扰素的实验研究[J].中医药信息，2004，(4):75-76.
[7] 〖JP2〗Fraunfelder FW.Epinastine hydrochloride for atopic disease[J].Drugs Today(Barc)，2004，40(8):677-683.
[8] 张桂芝.润燥止痒胶囊联合盐酸西替利嗪治疗老年性皮肤瘙痒病85例临床观察[J].中国皮肤性病学杂志，2013，27(11):1196-1197.
[9] 黄艳春，龚丽萍，杨美平.润燥止痒胶囊联合盐酸依匹斯汀胶囊治疗血虚风燥型慢性荨麻疹的疗效观察[J].中国皮肤性病学杂志，2011，25(11):193-195.

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[9]权哲,干慧慧,梅莉红,等.性病门诊老年患者304例临床分析[J].中国皮肤性病学杂志,2013,(04):378.

更新日期/Last Update: 2016-02-20