[1]蔡云雅,方红.皮肌炎/多发性肌炎86例的甲状腺功能分析[J].中国皮肤性病学杂志,2015,(04):365-367,374.[doi:10.13735/j.cjdv.1001-7089.201406204]
 CAI Yun ya,FANG Hong.Clinical Analysis of Thyroid Function on 86 Cases of Dermatomyositis/Polymyositis Patients[J].The Chinese Journal of Dermatovenereology,2015,(04):365-367,374.[doi:10.13735/j.cjdv.1001-7089.201406204]
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皮肌炎/多发性肌炎86例的甲状腺功能分析
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2015年04期
页码:
365-367,374
栏目:
临床经验
出版日期:
2015-04-01

文章信息/Info

Title:
Clinical Analysis of Thyroid Function on 86 Cases of Dermatomyositis/Polymyositis Patients
作者:
蔡云雅1方红2
1.浙江中医药大学附属第一医院皮肤科,浙江 杭州310006;2.浙江大学医学院附属第一医院皮肤科,浙江 杭州 310003
Author(s):
CAI Yunya1FANG Hong2
1.Department of Dermatology,First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;2.Department of Dermatology,First Affiliated Hospital of Zhejiang University,Hangzhou 310003,China
关键词:
皮肌炎多发性肌炎甲状腺激素病态综合征
Keywords:
DermatomyositisPolymyositisThyroidhormoneSick syndrome
分类号:
R 593.26;R 746
DOI:
10.13735/j.cjdv.1001-7089.201406204
文献标志码:
B
摘要:
目的探讨皮肌炎/多发性肌炎(DM/PM)合并甲状腺功能异常的临床特点及其意义。方法回顾性分析86例DM/PM患者的甲状腺功能检测指标及其临床资料,依据其甲状腺功能检测结果是否正常进行分组、比较。结果86例DM/PM患者中,甲状腺激素检测结果异常者54例(62.79%);其中甲状腺机能正常的病态综合征发生率最高(51.85%),其他依次为亚临床甲减、临床型甲减、亚临床甲亢、桥本甲状腺炎。与正常组相比,甲状腺激素异常组患者多见合并发热、胸膜炎/胸腔积液,也常出现CRP升高、低蛋白血症、血钙下降(P均<0.05)。结论DM/PM患者合并甲状腺激素异常的发生率高,其中尤以甲状腺机能正常的病态综合征最为多见。
Abstract:
ObjectiveTo investigate the clinical features and significance of dermatomyositis (DM)/polymyositis (PM) complicated with thyroid dysfunction.MethodsThe clinical and laboratory data of 86 patients with DM/PM were analyzed retrospectively.The data were compared between patients with and without thyroid dysfunction.ResultsFiftyfour cases(62.79%) were associated with thyroid dysfunction in all 86 patients.The most common subgroup of thyroid dysfunction was euthyroid sick syndrome (ESS) (51.85%),followed by subclinical hypothyroidism,clinical hypothyroidism,subclinical hyperthyroidism and Hashimoto′s thyroiditis.Compared with the group without thyroid dysfunction,DM/PM patients with thyroid dysfunction were more likely to have higher incidences of fever and pleuritis/pleural effusion,as well as higher levels of CRP,and lower levels of albumin and blood calcium(P<0.05).ConclusionThyroid dysfunction is common in DM/PM.ESS is most frequently seen.

参考文献/References:

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更新日期/Last Update: 2015-04-25