[1]修宁宁,辛青松,韩帅.艾滋病并发马尔尼菲青霉菌感染3例[J].中国皮肤性病学杂志,2015,(02):167-168.[doi:10.13735/j.cjdv.1001-7089.201540301]
 XIU Ning ning,XIN Qing song,HAN Shuai.AIDS patients infected with Penicillium Marneffei-clinical 3 Cases Report[J].The Chinese Journal of Dermatovenereology,2015,(02):167-168.[doi:10.13735/j.cjdv.1001-7089.201540301]
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艾滋病并发马尔尼菲青霉菌感染3例
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2015年02期
页码:
167-168
栏目:
性传播疾病
出版日期:
2015-02-01

文章信息/Info

Title:
AIDS patients infected with Penicillium Marneffei-clinical 3 Cases Report
作者:
修宁宁辛青松韩帅
广东省东莞康华医院,广东 东莞 523080
Author(s):
XIU NingningXIN QingsongHAN Shuai
Dongguan Kanghua Hospital,Guangdong 523080,China
关键词:
艾滋病马尔尼菲青霉菌
Keywords:
AIDSPenicillium marneffei
分类号:
R 512.91;R 519.2
DOI:
10.13735/j.cjdv.1001-7089.201540301
文献标志码:
B
摘要:
例1女,22岁,会阴部反复溃疡伴渗出液2月余,慢性贫血病容,面部可见散在分布疱疹,口唇黏膜破溃,双侧颈部可触及一肿大淋巴结。例2男,46岁,全身酸痛,乏力不适,后逐渐出现发热,T 39℃以上,前胸部可见散在分布皮下瘀点,右侧胸锁乳突肌后缘可触及数枚肿大淋巴结。例3女,40岁,无明显诱因出现发热,伴畏寒、寒颤,全身乏力、肌肉酸痛,四肢偶见瘀斑,脸部见散在分布红色皮疹,浅表淋巴结未触及肿大。3例均有发热、贫血、皮疹或溃疡、脾大等。实验室检查示外周血均呈三系减少,肝功:AST和(或)ALT升高,HIV抗体(+),血培养见马尔尼菲青霉菌等特征。均诊断为艾滋病并发马尔尼菲青霉菌感染。
Abstract:
The first patient was a woman aged 22 years old with repeated cankers and effusion in perineum.Anemia look and scattered herpes were seen on her face.Ulcers were ruptured in oral lips and bilateral cervical lymph nodes became enlarged on physical examination.The second patient was a 46 yearold man complaining of fatigue and discomfort throughout body with a temperature above 39℃.Scattered subcutaneous petechiae were seen in anterior part of chest and several enlarged lymph nodes could be touched in the right posterior border of sternocleidomastoid on physical examination.The last patient was a woman whose age was 40 years.The chief complaint was feeling chill and aches throughout body.Unprovoked fever,ecchymosis on limbs and scattered red rash were seen on the face on physical examination.Superficial enlarged lymph nodes were not touched.In all three patients,their clinical manifestation showed fever,anemia,rash,ulcers and enlarged spleen.And the Laboratory examination showed decrease of red blood cell,white blood cell and platelet,but the increase of alanine aminotransferase(ALT) and aspartate aminotransferase(AST).They all showed human immunodeficiency virus(HIV) antibody positive and Penicillium Marneffei from blood culture.They were all diagnosed as acquired immunodeficiency syndrome(AIDS) with Penicillium Marneffei.

参考文献/References:

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[2] Piehl MR,Kaplan RL,Haber MH.Disseminated penicilliosis in a patient with acquired immunodeficiency syndrome[J].Arch Pathol Lab Med,1988,112(12):1262-1264.
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[4] 赵国庆,冉玉平,向耘.中国大陆马尔尼菲青霉病的临床表现及流行病学特征的系统评价[J]中国真菌学杂志 2007,2(2):68-72.
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更新日期/Last Update: 2015-02-25