[1]王彩梅,汤洁,向志,等.甲损害在泛发性脓疱型银屑病中的临床意义[J].中国皮肤性病学杂志,2015,(01):44-46.[doi:10.13735/j.cjdv.1001-7089.2015.0044]
 WANG Cai mei,TANG Jie,XIANG Zhi,et al.Clinical Significance of Nail Involvement in Generalized Pustular Psoriasis[J].The Chinese Journal of Dermatovenereology,2015,(01):44-46.[doi:10.13735/j.cjdv.1001-7089.2015.0044]
点击复制

甲损害在泛发性脓疱型银屑病中的临床意义
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2015年01期
页码:
44-46
栏目:
临床经验
出版日期:
2015-01-01

文章信息/Info

Title:
Clinical Significance of Nail Involvement in Generalized Pustular Psoriasis
作者:
王彩梅1汤洁2向志2崔盘根2林麟2顾恒2陈敏2王宝玺2
1.宜兴市皮肤病医院,江苏 宜兴 214200;2.中国医学科学院皮肤病医院,江苏 南京 210042
Author(s):
WANG Caimei1TANG Jie2XIANG Zhi2CUI Pangen2LIN Lin2GU Heng2CHEN Min2WANG Baoxi2
1.Yixing Skin Disease Hospital,Yixing 214200,China;2.Institute of Dermatology,Chinese Academy of Medical Sciences & Peking Union Medical College,Nanjing 210042,China
关键词:
甲损害银屑病泛发性脓疱型临床分析
Keywords:
Nail involvement Psoriasisgeneralizedpustular Clinical analysis
分类号:
R 758.63
DOI:
10.13735/j.cjdv.1001-7089.2015.0044
文献标志码:
B
摘要:
目的探讨甲损害在泛发性脓疱型银屑病发病中的临床意义。方法回顾性分析2010年1月-2013年12月在中国医学科学院皮肤病研究所皮内科收治的206例泛发性脓疱型银屑病患者的临床资料,比较伴有和不伴有甲损害患者的一般资料、实验室检查结果及治疗方法和疾病预后等临床资料。结果男性患者甲损害多于女性患者,有甲损害组患者平均年龄、体重均明显高于无甲损害组患者(P均<0.05);甲损害组患者住院期间体温降至正常时间、无新发脓疱时间及住院天数明显高于无甲损害组患者(P均<0.05)。结论泛发性脓疱型银屑病患者伴有甲损害可能预示病情较严重,对于评估病情及临床用药具有指导意义。
Abstract:
ObjectiveTo explore the clinical significance of nail involvement in generalized pustular psoriasis (GPP).MethodsWe retrospectively analyzed the clinical data of 206 cases of GPP who were hospitalized in Institute of Dermatology,Chinese Academy of Medical Sciences & Peking Union Medical College from January 2000 to December 2013 and compared the difference on the general information,laboratory results,treatment and disease prognosis of those with nail involvement and without.ResultsOf these patients,male patients were more common with nail involvement,the mean age and body weight of patients with nail involvement were significantly higher than those without nail involvement,respectively P all<0.05.The time of temperature drop to normal,the time of no new pustules and length of stay were significantly higher than those without nail involvement,respectively P all<0.05.ConclusionNail involvement in GPP is a predictor for a severe disease course,which has a guiding significance to the evaluation of disease and the clinical treatment.

参考文献/References:

[1] 廖金英,雷梅珍,罗娅,等.泛发性脓疱型银屑51例临床分析[J].医学临床研究,2013,30(5):899-901.
[2] Armesto S,Esteve A,CotoSegura P,et al.Nail psoriasis in individuals with psoriasis vulgaris:A study of 661 patients[J].Actas Dermosifiliogr,2011,102(5):365-372.
[3] 王刚,高天文,刘玉峰.脓疱性银屑病76例临床分析[J].临床皮肤科杂志,2004,33(12):717-720.
[4] 王豫平,刘鸿伟,张书岭,等.泛发性脓疱型银屑病患者发热和白细胞升高与病情的相关性[J].临床皮肤科杂志,2001,10(30):308.

相似文献/References:

[1]唐娟,张晓艳,宋佩华,等.寻常性银屑病患者皮损及外周血单一核细胞中IL-17A的表达[J].中国皮肤性病学杂志,2012,(08):689.
 TANG Juan,ZHANG Xiao-yan,SONG Pei-hua,et al.Expression of IL-17A in Involved Lesions and Blood Mononuclear Cells of Patients with Psoriaisis[J].The Chinese Journal of Dermatovenereology,2012,(01):689.
[2]戴莎,王秀丽,宋心葵,等.银屑病患者410例合并代谢综合征分析[J].中国皮肤性病学杂志,2012,(08):700.
 DAI Sha,WANG Xiu-li,SONG Xin-kui,et al.Analysis of 410 Cases of Psoriasis Patients with Metabolic Syndrome[J].The Chinese Journal of Dermatovenereology,2012,(01):700.
[3]谢韶琼,汪青良,宋勋,等.凉血润肤汤治疗寻常性银屑病42例疗效观察[J].中国皮肤性病学杂志,2012,(08):743.
 XIE Shao-qiong,WANG Qing-liang,SONG Xun,et al.Clinical Observation of Liangxierunfu Decoction on 42 Cases of Psoriasis Vulgaris[J].The Chinese Journal of Dermatovenereology,2012,(01):743.
[4]广维,朱红,姚树兰,等.伊那西普治疗银屑病的十年回顾[J].中国皮肤性病学杂志,2012,(08):745.
 GUANG Wei,ZHU Hong,YAO Shu-lan,et al.A 10-year Review of Etanercept in the Treatment of Psoriasis[J].The Chinese Journal of Dermatovenereology,2012,(01):745.
[5]史航,刘晓明,林熙然,等.银屑病发病与创伤愈合机制的比较[J].中国皮肤性病学杂志,2012,(08):748.
 SHI Hang,LIU Xiao-ming,LIN Xi-ran.A Comparison on Pathogenesis of Psoriasis and Mechanism of Wound Healing[J].The Chinese Journal of Dermatovenereology,2012,(01):748.
[6]刘晓洁,张峻岭,刘雪,等.头皮银屑病和脂溢性皮炎的皮肤镜特征分析[J].中国皮肤性病学杂志,2015,(01):36.[doi:10.13735/j.cjdv.1001-7089.2015.0036]
 LIU Xiao jie,ZHANG Jun ling,LIU Xue,et al.Analysis of Dermoscopic Criteria for Scalp Psoriasis and Scalp Seborrheic Dermatitis[J].The Chinese Journal of Dermatovenereology,2015,(01):36.[doi:10.13735/j.cjdv.1001-7089.2015.0036]
[7]李珺莹,李红.酪氨酸激酶及其抑制剂与免疫性皮肤病的研究进展[J].中国皮肤性病学杂志,2015,(01):93.[doi:10.13735/j.cjdv.1001-7089.2015.0093]
 LI Jun ying,LI Hong.Tyrosine Kinases and its Inhibitors in Immune Dermatologic Diseases[J].The Chinese Journal of Dermatovenereology,2015,(01):93.[doi:10.13735/j.cjdv.1001-7089.2015.0093]
[8]段茜,程燕,储蕾,等.银屑病与高血压病的相关性分析[J].中国皮肤性病学杂志,2015,(02):143.[doi:10.13735/j.cjdv.1001-7089.201404140]
 DUAN Xi,CHENG Yan,CHU Lei,et al.The Correlation between Psoriasis and Hypertension[J].The Chinese Journal of Dermatovenereology,2015,(01):143.[doi:10.13735/j.cjdv.1001-7089.201404140]
[9]杨颜龙,张禁,易松柏,等.阿维A胶囊联合复方甘草酸苷注射液治疗红皮病型银屑病30例临床观察[J].中国皮肤性病学杂志,2015,(02):217.[doi:10.13735/j.cjdv.1001-7089.201403167]
 YANG Yan long,ZHANG Jin,YI Song bai,et al.Clinical Observation of 30 Acitretin Capsules Combine with Compound Glycyrrhizin Injection in the Treatment of Patients with Erythrodermic Psoriasis[J].The Chinese Journal of Dermatovenereology,2015,(01):217.[doi:10.13735/j.cjdv.1001-7089.201403167]
[10]孙景英,普雄明,吴卫东.CXCL9和Smad3在新疆维吾尔族寻常性银屑病患者皮损中的表达[J].中国皮肤性病学杂志,2015,(03):242.[doi:10.13735/j.cjdv.1001-7089.201407083]
 SUN Jing ying,PU Xiong ming,WU Wei dong.The Expression of CXCL9 and Smad3 in Psoriasis Vulgaris of Xinjiang Uyghur Patients[J].The Chinese Journal of Dermatovenereology,2015,(01):242.[doi:10.13735/j.cjdv.1001-7089.201407083]

备注/Memo

备注/Memo:
[基金项目]卫生公益性行业科研专项经费项目(201002016)
更新日期/Last Update: 2015-01-25