[1]黎华莉,赵金柳,蒋茵,等.甲真菌病与甲银屑病病甲皮肤镜图像特征对比分析[J].中国皮肤性病学杂志,2020,(11):1272-1276.[doi:10.13735/j.cjdv.1001-7089.202002103]
　LI Huali,ZHAO Jinliu,JIANG Yin,et al.Comparative Analysis of Dermatoscope Image Characteristics in Patients with Onychomycosis and Nail Psoriasis[J].The Chinese Journal of Dermatovenereology,2020,(11):1272-1276.[doi:10.13735/j.cjdv.1001-7089.202002103]
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甲真菌病与甲银屑病病甲皮肤镜图像特征对比分析()
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2020年11期
页码:
1272-1276
栏目:
临床经验
出版日期:
2020-11-01

文章信息/Info

Title:
Comparative Analysis of Dermatoscope Image Characteristics in Patients with Onychomycosis and Nail Psoriasis
文章编号:
1001-7089(2020)11-1272-05
作者:
黎华莉1; 赵金柳1; 蒋茵2; 肖文1
1.柳州市工人医院皮肤科,广西 柳州 545005; 2.柳州市工人医院风湿免疫科,广西 柳州 545005
Author(s):
LI Huali1; ZHAO Jinliu1; JIANG Yin2; XIAO Wen1
1.Department of Dermatology,Liuzhou Worker's Hospital,Liuzhou 545005,China; 2.Department of Rheumatology and Immunology,Liuzhou Worker's Hospital,Liuzhou 545005,China
关键词:
甲真菌病;  甲银屑病;  皮肤镜;  图像
Keywords:
Onychomycosis;  Nail psoriasis;  Dermatoscope;  Image
分类号:
R 758.72
DOI:
10.13735/j.cjdv.1001-7089.202002103
文献标志码:
B
摘要:
目的 探讨甲真菌病与甲银屑病病甲皮肤镜图像特征差异。方法 回顾性分析本院2017年1月-2019年9月收治的甲真菌病与甲银屑病病患者各256例临床资料,分析病甲皮肤镜图像特征和临床亚型资料,比较甲真菌病与甲银屑病病甲皮肤镜图像特征。结果 ①甲银屑病和甲真菌病患者一般资料比较差异无统计学意义(P>0.05); ②远端甲下型甲真菌病患者边缘锯齿改变和纵行条纹比例显著高于其他亚型(P<0.05); 全甲型甲真菌病患者锥形角化比例显著高于其他亚型(P<0.05); ③寻常性和关节病型甲银屑病患者油滴改变比例显著高于其他亚型(P<0.05); 脓疱型甲银屑病患者甲床毛细血管扩张比例显著高于其他亚型(P<0.05); ④甲真菌病和甲银屑病共同特征发生率比较差异无统计学意义(P>0.05)。结论 甲真菌病与甲银屑病均存在各自特殊病甲皮肤镜图像特征,但两者在甲板增厚、甲板剥离及趾/指甲变色发生频率方面较为接近。
Abstract:
Objective To investigate the image characteristics differences in patients with onychomycosis and nail psoriasis.Methods Clinical data of 256 patients with onychomycosis and nail psoriasis were retrospectively chosen in the period from January 2017 to September 2019.The image features and clinical subtypes of the dermatoscope of nail were analyzed and the characteristics of nail dermoscopy between onychomycosis and nail psoriasis were compared.Results ①There was no significant difference in the general data between patients with onychomycosis and nail psoriasis(P>0.05).②The proportion of edge jagged changes and vertical stripes in patients with distal subungual onychomycosis were significantly higher than other subtypes(P<0.05).The proportion of keratonization in patients with all nail onychomycosis were significantly higher than other subtypes(P<0.05).③The proportion of oil drop changes in patients with vulgaris and arthropathy psoriasis were significantly higher than other subtypes(P<0.05).The proportion of capillaries expansion in nail bed of patients with pustular psoriasis were significantly higher than other subtypes(P<0.05).④There was no significant difference in the incidence of common characteristics between patients with onychomycosis and nail psoriasis(P>0.05).Conclusion Both onychomycosis and nail psoriasis have their own special nail dermatoscopic features,but they are similar in the frequency of deck thickening,deck peeling and toe / nail discoloration.

参考文献/References:

[1] Bhat YJ,Mir MA,Keen A,et al.Onychoscopy:an observational study in 237 patients from the Kashmir Valley of North India[J].Dermatol Pract Concept,2018,8(4):283-291.
[2] Maatouk I,Haber R,Benmehidi N.Onychoscopic evaluation of distal and lateral subungual onychomycosis:A cross-sectional study in Lebanon[J].Curr Med Mycol,2019,5(2):41-44.
[3] Abdallah NA,Said M,Mahmoud MT,et al.Onychomycosis:Correlation between the dermoscopic patterns and fungal culture[J].J Cosmet Dermatol,2019,10(9):211-218.
[4] Nada EEA,El Taieb MA,El-Feky MA,et al.Diagnosis of onychomycosis clinically by nail dermoscopy versus microbiological diagnosis[J].Arch Dermatol Res,2019,14(11):1037-1042.
[5] Rich P,Scher RK.Nail psoriasis severity index:a useful tool for evaluation of nail psoriasis[J].J Am Acad Dermatol,2003,49(2):206-212.
[6] 孙振燕,张思平,章婧,等.甲真菌病皮肤镜表现及模式分析[J].中华皮肤科杂志,2018,51(11):812-814.
[7] Ramos Pinheiro R,Dias Domingues T,Sousa V,et al.A comparative study of onychomycosis and traumatic toenail onychodystrophy dermoscopic patterns[J].J Eur Acad Dermatol Venereol,2019,33(4):786-792.
[8] Yorulmaz A,Yalcin B.Dermoscopy as a first step in the diagnosis of onychomycosis[J].Postepy Dermatol Alergol,2018,35(3):251-258.
[9] Chetana K,Menon R,David BG.Onychoscopic evaluation of onychomycosis in a tertiary care teaching hospital:a cross-sectional study from South India[J].Int J Dermatol,2018,57(7):837-842.
[10] Nargis T,Pinto M,Shenoy MM,et al.Dermoscopic features of distal lateral subungual onychomycosis[J].Indian Dermatol Online J,2018,9(1):16-19.
[11] Kaynak E,Göktay F,Güne�瘙塂 P,et al.The role of dermoscopy in the diagnosis of distal lateral subungual onychomycosis[J].Arch Dermatol Res,2018,310(1):57-69.
[12] Lencastre A,Pinheiro R,Cunha N.A study of dermoscopic features of nail psoriasis:the pseudo-pseudo-fiber sign[J].Postepy Dermatol Alergol,2018,35(6):649.
[13] Golińska J,Sar-Pomian M,Rudnicka L.Dermoscopic features of psoriasis of the skin,scalp and nails-a systematic review[J].J Eur Acad Dermatol Venereol,2019,33(4):648-660.
[14] Hashimoto Y,Uyama M,Takada Y,et al.Dermoscopic features of nail psoriasis treated with biologics[J].J Dermatol,2017,44(5):538-541.
[15] Kaya I·slamolu ZG,Uysal E,Demirba�瘙塂 A,et al.Evaluating nail thickness and stiffness with shear-wave elastography in nail psoriasis:A preliminary study[J].Skin Res Technol,2020,26(1):45-49.
[16] Rigopoulos D,Baran R,Chiheb S,et al.Recommendations for the definition,evaluation,and treatment of nail psoriasis in adult patients with no or mild skinpsoriasis:A dermatologist and nail expert group consensus[J].J Am Acad Dermatol,2019,81(1):228-240.
[17] Mease PJ,Palmer JB,Hur P,et al.Utilization of the validated Psoriasis Epidemiology Screening Tool to identify signs and symptoms of psoriatic arthritis among those with psoriasis:a cross-sectional analysis from the US-based Corrona Psoriasis Registry[J].J Eur Acad Dermatol Venereol,2019,33(5):886-892.

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备注/Memo

备注/Memo:
[通信作者] 肖文,E-mail:196821xw@sina.com
更新日期/Last Update: 2020-11-16