[1]谭艳平,龚存林,高捷敏,等.以阴道出血为首发症状的宫颈硬下疳1例[J].中国皮肤性病学杂志,2018,(02):185-186.[doi:10.13735/j.cjdv.1001-7089.201708058]
 TAN Yanping,GONG Cunlin,GAO Jiemin,et al.A Case of Cervical Ulcerating Sclerosis with Vaginal Bleeding as Intial Symptom[J].The Chinese Journal of Dermatovenereology,2018,(02):185-186.[doi:10.13735/j.cjdv.1001-7089.201708058]
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以阴道出血为首发症状的宫颈硬下疳1例
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2018年02期
页码:
185-186
栏目:
性传播疾病
出版日期:
2018-02-01

文章信息/Info

Title:
A Case of Cervical Ulcerating Sclerosis with Vaginal Bleeding as Intial Symptom
作者:
谭艳平龚存林高捷敏付宾
江西省妇幼保健院皮肤性病科,江西 南昌330006
Author(s):
TAN YanpingGONG CunlinGAO JieminFU Bin
Department of Dermatology, Jiangxi Maternal and Child Health Hospital, Nanchang 330006, China
关键词:
阴道流血 宫颈 硬下疳 一期梅毒
Keywords:
Vaginal bleeding Cervical Ulcerating sclerosis Primary syphilis
分类号:
R 759.1
DOI:
10.13735/j.cjdv.1001-7089.201708058
文献标志码:
B
摘要:
患者女,26岁。阴道不规则流血2周。查体:宫颈可见一鹌鹑蛋大小溃疡面,表面渗血; 双侧腹股沟无淋巴结肿大; 躯干、四肢未见红斑和脱屑。实验室检查:TPPA(+),TRUST 1:64(+); TP-IgM(+); HIV抗体阴性; HSV-Ⅰ IgG(+),HSV-Ⅱ IgG(+),HSV-Ⅰ IgM(-),HSV-Ⅱ IgM(-); HSV-Ⅱ PCR(分泌物)阴性; 宫颈溃疡表面分泌物暗视野检查梅毒苍白螺旋体(+); 电子阴道镜组织病理检查示:考虑黏膜炎症性改变。诊断:一期梅毒,宫颈硬下疳。予以苄星青霉素240万U分两侧臀部肌注,1次/周,连用2次,皮损4周后消退,复查TP-IgM转阴。 定期复查6个月时,TRUST转阴,目前随访中。
Abstract:
A 26 years female, presented with vaginal bleeding 2 weeks.Examination showed that there was a painless ulcers on the cervical,quail egg sized, and most of them had blood oozing.Enlarged lymph nodes were not found on the two sides of groins, and no erythema and desquamation were found on torso and limbs either.Laboratory tests had results as follow: TPPA(+), TRUST 1:64(+); TP-IgM(+); HIV(-); HSV-Ⅰ IgG(+), HSV-Ⅱ IgG(+), HSV-Ⅰ IgM(-), HSV-Ⅱ IgM(-); HSV-Ⅱ PCR(-).Using TP-darkfield microscopic found TP in the secretions of Cervical ulcer; biopsy under electronic colposcope indicated the change of mucosal inflammatory.Therefore, the diagnosis is primary syphilis and cervical ulcerating sclerosis.Benzathine penicillin G 2.4 MU injections were given to each buttock once a week for 2 weeks.After 4 weeks chancres disappear, and TP-IgM was reviewed to be overcast.After 6 months TRUST overcast.A diagnosis of rectum ulcerating sclerosis was established.

参考文献/References:

[1] 傅宗芬, 严东成.早期梅毒血清学及暗视野检查梅毒螺旋体结果分析[J].临床皮肤科杂志, 2002, 31(3):167.
[2] Schmidt BL, Edjlalipour M, Luger A.Comparative evaluation of nine different enzyme-linked immunosorbent assays for determination of antibodies against Treponema pallidum in patients with primary syphilis[J].J Clin Microbiol, 2000, 38(3): 1279-1282.
[3] 张永乐,章松平,马兰,等.检测早期梅毒螺旋体感染的4种方法比较[J].中国皮肤性病学杂志, 2008, 22(2): 118.

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更新日期/Last Update: 1900-01-01