[1]李杨,王舒,李福秋,等.砷角化症伴高分化鳞状细胞癌1例[J].中国皮肤性病学杂志,2016,(11):1163-1164.[doi:10.13735/j.cjdv.1001-7089.201604031]
 LI Yang,WANG Shu,LI Fu-qiu,et al.A Case of Arsenical Keratosis with High Differentiated Squamous Cell Carcinoma[J].The Chinese Journal of Dermatovenereology,2016,(11):1163-1164.[doi:10.13735/j.cjdv.1001-7089.201604031]
点击复制

砷角化症伴高分化鳞状细胞癌1例
分享到:

《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2016年11期
页码:
1163-1164
栏目:
病例报告
出版日期:
2016-11-01

文章信息/Info

Title:
A Case of Arsenical Keratosis with High Differentiated Squamous Cell Carcinoma
作者:
李杨王舒李福秋姚春丽范丹丹汪华阳
吉林大学第二医院,吉林 长春 130000
Author(s):
LI YangWANG ShuLI Fu-qiuYAO Chun-liFAN Dan-danWANG Hua-yang
The Second Hospital of Jilin University,Changchun 130000,China
关键词:
角化症 鳞状细胞癌
Keywords:
Arsenical Keratosis Squamous carcinoma
分类号:
R 739.5
DOI:
10.13735/j.cjdv.1001-7089.201604031
文献标志码:
B
摘要:
患者女,51岁。手足角化性丘疹10年,右足趾间溃疡1年。手部丘疹组织病理示表皮角化过度,表皮突向下不规则延伸; 右足溃疡处癌组织浸润性生长,可见显著核多形性及有丝分裂。诊断:砷角化症; 高分化鳞状细胞癌。在随访中。
Abstract:
A 51-year-old female presented with keratotic papules on the hands and feet for 10 years, and appeared a interdigital ulcer for 1 year. A hand skin biopsy revealed hyperkeratosis in the epidermis and irregular rete ridges extending into the dermis. Furthermore, the interdigital ulcer histologically featured invasive growth of tumur with marked nuclear pleomorphism and mitosis in cells. A arsenical keratosis and high differentiated squamous cell carcinoma were diagnosed. The patient remains in the clinical follow-up.

参考文献/References:

[1] 张瑞丽,任虹.砷角化病并发鳞状细胞癌1例[J].中国皮肤性病学杂志,2011,25(9):705-706.
[2] 高萃苹,杜志芹,肖尹,等.慢性医源性砷角化病1例[J].中国皮肤性病学杂志,2012,26(10):939-940.
[3] Thang ND.Bidirectional functions of arsenic as a carcinogen and an anti-cancer agent in human squamous cell carcinoma[J].PLoS One,2014,9(5):e96945.
[4] 高广程.砷角化病并多发鳞状细胞癌死亡1例[J].中国麻风皮肤病杂志,2010,26(10):741-742.
[5] Ahsan H,Steinmaus C.Use of arsenical skin lesions to predict risk of in-ternal cancer:implications for prevention and future research [J].Am J Ep-idemiol,2013,177(3):213-216.
[6] Hsu L.Use of arsenic-induced palmoplantar hyperkeratosis and skin cancers to predict risk of subsequent internal malignancy[J].Am J Epide- miol,2013,177(3):202-212.

相似文献/References:

[1]周优优,高明阳.砷致HaCaT恶性转化细胞热休克蛋白27水平变化的观察[J].中国皮肤性病学杂志,2015,(02):122.[doi:10.13735/j.cjdv.1001-7089.201407076]
 ZHOU You you,GAO Ming yang.The Change of HSP27 in HaCaT Malignant Transformation Cell Induced by Arsenic[J].The Chinese Journal of Dermatovenereology,2015,(11):122.[doi:10.13735/j.cjdv.1001-7089.201407076]
[2]安建博,牛永权,赵桂鹏,等.饮水型砷中毒地区水三价砷含量与皮肤病变的相关性分析[J].中国皮肤性病学杂志,2014,(10):1004.[doi:10.13735/j.cjdv.1001-7089.2014.1004]
 AN Jian-bo,NIU Yong-quan,ZHAO Gui-peng,et al.Analysis of the Correlation between Trivalent Arsenic Content in Drinking Water and Skin Lesions of Arsenic Poisoning[J].The Chinese Journal of Dermatovenereology,2014,(11):1004.[doi:10.13735/j.cjdv.1001-7089.2014.1004]

备注/Memo

备注/Memo:
[通讯作者] 李福秋,E-mail:lifuqiu@medmail.com.cn
更新日期/Last Update: 2016-11-01