[1]黄桃源,杨文林.急性时相反应及凝血/纤溶系统参与慢性荨麻疹发病的研究进展[J].中国皮肤性病学杂志,2014,(01):84-86.
 HUANG Tao-yuan,YANG Wen-lin.Acute-phase Response and Coagulation/Fibrinolysis in the Pathogenesis of Chronic Urticaria[J].The Chinese Journal of Dermatovenereology,2014,(01):84-86.
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急性时相反应及凝血/纤溶系统参与慢性荨麻疹发病的研究进展
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《中国皮肤性病学杂志》[ISSN:1001-7089/CN:61-1197/R]

卷:
期数:
2014年01期
页码:
84-86
栏目:
综述
出版日期:
2014-01-20

文章信息/Info

Title:
Acute-phase Response and Coagulation/Fibrinolysis in the Pathogenesis of Chronic Urticaria
作者:
黄桃源杨文林
广州医科大学附属第二医院皮肤科,广东 广州 510260
Author(s):
HUANG Tao-yuan YANG Wen-lin
(Department of Dermatology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China)
关键词:
慢性荨麻疹 急性时相反应 血液凝固因子
Keywords:
Chronic urticaria Acute-phase response Blood coagulation factors
分类号:
R 758.24
文献标志码:
A
摘要:
慢性荨麻疹的病因复杂且仍然未完全清楚。已有文献报道慢性荨麻疹患者部分急性时相标记物水平升高,提示急性时相反应有可能参与了慢性荨麻疹的发病; 另一方面,已证实慢性荨麻疹患者内、外凝血途径激活,多种凝血因子水平升高,并与慢性荨麻疹症状严重程度相关; 在多种疾病中,急性时相反应与凝血/纤溶功能关系密切。本文就急性时相反应及凝血/纤溶系统参与慢性荨麻疹发病的国内外研究现状与进展作一综述。
Abstract:
The exact pathogenic mechanism of chronic urticaria(CU)is complex and unclear.It has been shown that concentrations of circulating acute-phase response biomarkers are elevated in chronic urticaria, suggesting the involvement of acute-phase response in the development of CU.Recently, it has been demonstrated that the activation of the coagulation/fibrinolysis and the increased level of coagulation factors may be correlated with the disease severity.The association of acute-phase response with coagulation/fibrinolysis has been shown in many diseases.This review summarized the recent advances and developments of chronic urticaria about acute-phase response and coagulation/fibrinolysis.

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备注/Memo

备注/Memo:
[作者单位] 广州医科大学附属第二医院皮肤科,广东 广州 510260 [通讯作者] 杨文林,E-mail:yangwenlin@21cn.com
更新日期/Last Update: 2014-01-20